Concentrations of perfluoroalkyl substances in foods and the dietary exposure among Taiwan general population and pregnant women.
Concentrations of perfluoroalkyl substances in foods and the dietary exposure among Taiwan general population and pregnant women.
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DOI：
10.1016/j.jfda.2017.12.011
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发表时间：
2018-07
影响因子：
3.6
通讯作者：
Chia-Yang Chen
中科院分区：
文献类型：
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作者：
Wen-Ling Chen;Fang-Yu Bai;Ying-Chia Chang;Pau-Chung Chen;Chia-Yang Chen
本研究利用超高效液相色谱-串联质谱法（ultra-performance liquid chromatography-tandem mass spectrometry，UPLC-MS）分析台湾地区谷物、肉类、海产品、蛋类、猪肝和牛奶中的五种全氟羧酸（perfluorocarboxylic acids，PFCAs）和两种全氟磺酸（perfluorosulfonate acids，PFCAs），并分别以人均消费量和问卷调查评估一般人群和孕妇的膳食暴露量。在几乎所有的样品中都发现了全氟辛酸（PFOA）和10-12个碳的全氟辛酸，在大米和猪肝中的浓度相当高，高达283纳克/克（猪肝中的PFOA）;水平比以前的报告高出两到三个数量级。全氟辛烷磺酸（PFOS）是最常提及的全氟烷基物质，除牛肉、猪肝和一些海产品（检测频率：100%，GM：0.05-3.52纳克/克）外，在许多食品中很少检测到<0.4纳克/克的全氟辛烷磺酸（在大米、面粉、猪肉、鸡肉、鲑鱼、鱿鱼、鸡蛋和牛奶中的检测频率<20%）。与西方国家的人群相比，台湾人暴露于更多的全氟己酸、全氟辛酸、全氟癸酸和全氟十一烷酸（11.2、85.1、44.2和4.45 ng/kg b.w./主要原因是食品中的污染物含量较高。95百分位数的孕妇暴露于8.0微克PFOA/人/天，是因为她们经常食用猪肝。
This study quantified five perfluorocarboxylic acids (PFCAs) and two perfluorosulfonic acids in cereals, meats, seafood, eggs, pork liver, and milk in Taiwan using ultra-performance liquid chromatography-tandem mass spectrometry and evaluated the dietary exposure of the general population and pregnant women using per capita consumption and a questionnaire, respectively. Perfluorooctanoic acid (PFOA) and PFCAs of 10–12 carbons were found in almost all of the samples in considerable concentrations in rice and pork liver, reaching as high as 283 ng/g (PFOA in pork liver); the levels are two to three orders of magnitude higher than previous reports. Perfluorooctane sulfonate (PFOS), the most frequently mentioned perfluoroalkyl substance, was rarely detected in many food items (detection frequencies <20% in rice, flour, pork, chicken, salmon, squid, eggs, and milk) at <0.4 ng/g, except for beef, pork liver and some seafood (detection frequencies: 100%, GMs: 0.05–3.52 ng/g). Compared to populations in Western countries, people in Taiwan are exposed to much more perfluorohexanoic acid, PFOA, perfluorodecanoic acid, and perfluoroundecanoic acid (11.2, 85.1, 44.2, and 4.45 ng/kg b.w./day, respectively), mainly due to the higher contaminations in food. The exposure of 8.0 μg PFOA/person/day in the 95 percentile of pregnant women was due to their frequent consumption of pork liver.