Serum Anti-Myelin-Associated Glycoprotein Antibodies in Egyptian Autistic Children
Serum Anti-Myelin-Associated Glycoprotein Antibodies in Egyptian Autistic Children
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DOI：
10.1177/0883073808319321
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发表时间：
2008-12-01
影响因子：
1.9
通讯作者：
Ei-Saned, Mohamed Farouk
中科院分区：
文献类型：
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作者：
Mostafa, Gehan Ahmed;El-Sayed, Zeinab Awad;Ei-Saned, Mohamed Farouk
对大脑的自身免疫可能在自闭症患者的亚组中发挥致病作用。本文对32例孤独症和32例健康儿童进行了血清抗髓磷脂相关糖蛋白抗体的检测，并对其与自身免疫家族史的关系进行了研究。孤独症儿童血清抗髓磷脂相关糖蛋白抗体水平显著高于健康儿童(2100和1138[87.5]Buhlmann单位，P
Autoimmunity to brain could play an etiopathogenic role in a Subgroup of autistic patients. The frequency of serum anti-myelin-associated glycoprotein antibodies, as an index for autoimmunity to brain, and their relation to family history of autoimmunity were investigated in 32 autistic and 32 healthy matched children. Autistic children had significantly higher serum anti-myelin-associated glycoprotein antibodies than healthy children (2100 [1995] and 1138 [87.5] Buhlmann titre unit, P