Fish and shellfish consumption in relation to death from myocardial infarction among men in Shanghai, China.
Fish and shellfish consumption in relation to death from myocardial infarction among men in Shanghai, China.
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DOI：
10.1093/aje/154.9.809
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发表时间：
2001-11
影响因子：
5
通讯作者：
Jian‐Min Yuan;Ronald K. Ross;Yu-Tang Gao;Mimi C. Yu
中科院分区：
文献类型：
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作者：
Jian‐Min Yuan;Ronald K. Ross;Yu-Tang Gao;Mimi C. Yu
1986年至1989年，中国上海18，244名年龄在45-64岁的男性参加了一项饮食与癌症的前瞻性研究。所有参与者都完成了面对面的结构化访谈，并提供了血液和尿液样本。截至1998年9月1日，确定了113例急性心肌梗死死亡。在对年龄、总能量摄入量和已知的心血管疾病风险因素进行调整后，每周食用≥ 200 g鱼/贝类的男性与每周食用<50 g的男性相比，致命性急性心肌梗死的相对风险为0.41（95%置信区间：0.22，0.78）。同样，从海鲜中摄取n-3脂肪酸也与心肌梗死死亡率降低显著相关。饮食中的海鲜和n-3脂肪酸摄入量与中风或缺血性心脏病（急性心肌梗死除外）的死亡风险降低无关。然而，在研究人群中观察到与每周鱼类/贝类摄入量相关的总死亡率降低约20%（相对风险= 0.79，95%置信区间：0.69，0.91）。这些前瞻性数据表明，在中国上海，每周吃鱼和贝类可以降低中老年男性致命性心肌梗死的风险。
Between 1986 and 1989, 18,244 men aged 45-64 years in Shanghai, China, participated in a prospective study of diet and cancer. All participants completed an in-person, structured interview and provided blood and urine samples. As of September 1, 1998, 113 deaths from acute myocardial infarction were identified. After analyses were adjusted for age, total energy intake, and known cardiovascular disease risk factors, men who consumed >or=200 g of fish/shellfish per week had a relative risk of 0.41 (95% confidence interval: 0.22, 0.78) for fatal acute myocardial infarction compared with men consuming <50 g per week. Similarly, dietary intake of n-3 fatty acids derived from seafood also was significantly associated with reduced mortality from myocardial infarction. Neither dietary seafood nor n-3 fatty acid intake was associated with a reduced risk of death from stroke or ischemic heart disease other than acute myocardial infarction. However, approximately a 20% reduction in total mortality associated with weekly fish/shellfish intake was observed in the study population (relative risk = 0.79, 95% confidence interval: 0.69, 0.91). These prospective data suggest that eating fish and shellfish weekly reduces the risk of fatal myocardial infarction in middle-aged and older men in Shanghai, China.