In vitro natamycin susceptibility of ocular isolates of Fusarium and Aspergillus species:: Comparison of commercially formulated natamycin eye drops to pharmaceutical-grade powder

In vitro natamycin susceptibility of ocular isolates of Fusarium and Aspergillus species:: Comparison of commercially formulated natamycin eye drops to pharmaceutical-grade powder
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DOI:
10.1128/jcm.00610-08
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发表时间:
2008-10-01
影响因子:
9.4
通讯作者:
Fothergill, A. W.
Fothergill, A. W.
中科院分区:
医学2区
文献类型:
--
作者:
Lalitha, P.;Vijaykumar, R.;Fothergill, A. W.

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临床和实验室标准研究所药敏方法禁止使用药物制剂,但获得纯粉末很困难。通过使用粉末和药房滴眼剂制剂评估那他霉素对从角膜炎中分离出的曲霉属和镰刀菌属菌株的活性。滴眼剂制剂可能是测试那他霉素活性的可行选择。
The Clinical and Laboratory Standards Institute susceptibility method prohibits the use of pharmacy preparations, but obtaining pure powders is difficult. The activity of natamycin against isolates of Aspergillus and Fusarium species isolated from keratitis was assessed by using both powder and pharmacy eye drop preparations. Eye drop preparations may be a viable option for testing natamycin activity.