Clinical prediction of survival is more accurate than the Karnofsky performance status in estimating life span of terminally ill cancer patients.
Clinical prediction of survival is more accurate than the Karnofsky performance status in estimating life span of terminally ill cancer patients.
复制标题
在估计末期癌症患者的寿命时，临床生存预测比卡诺夫斯基表现状态更准确。
DOI：
10.1016/0959-8049(94)90289-5
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发表时间：
1994
影响因子：
8.4
通讯作者：
D. Amadori
中科院分区：
文献类型：
--
作者：
M. Maltoni;O. Nanni;S. Derni;M. Innocenti;L. Fabbri;N. Riva;R. Maltoni;D. Amadori
预测晚期癌症患者的生存可以帮助告知患者及其家人，规划治疗和援助模式，并正确利用现有资源。临床生存预测(CPS)和卡诺夫斯基表现状态(KPS)是文献中已经描述的两个因素。我们研究的目的是验证它们各自对实际存活率的预测价值。在我们对100名连续患者的研究中，CPS获得了比先前报道的更高的预测准确性(与实际生存的相关系数=0.51)，也比单独使用KPS获得的预测准确性(相关系数=0.37)更高。预计生存时间和预期生存时间之间的中位数差异仅为1周。通过整合在更大的前瞻性多中心研究中研究的其他预后因素，结果的预测性可以进一步提高。
Predicting the survival of terminally ill cancer patients can help in informing patients and their families, in programming therapy and assistance models, and in utilising existing resources correctly. Clinical prediction of survival (CPS) and Karnofsky performance status (KPS) are two factors which have already been described in the literature. The aim of our study was to verify their respective predictive value with regard to actual survival. In our study of 100 consecutive patients, the CPS obtained a higher prediction accuracy than that reported previously (correlation coefficient with actual survival = 0.51) and than that obtained with KPS alone (correlation coefficient = 0.37). The median difference between predicted and expected survival was only 1 week. The resultant predictivity could be further improved by integrating other prognostic factors studied in larger prospective, multicentric studies.