Clinical Characterization of Canine Acanthomatous Ameloblastoma (CAA) in 263 dogs and the Influence of Postsurgical Histopathological Margin on Local Recurrence
Clinical Characterization of Canine Acanthomatous Ameloblastoma (CAA) in 263 dogs and the Influence of Postsurgical Histopathological Margin on Local Recurrence
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DOI：
10.1177/0898756417734312
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发表时间：
2017-12-01
影响因子：
1
通讯作者：
Soukup, Jason
中科院分区：
文献类型：
--
作者：
Goldschmidt, Stephanie L.;Bell, Cindy M.;Soukup, Jason
犬棘皮瘤性成釉细胞瘤(CAA)是犬最常见的牙源性肿瘤。这项回顾研究评估了263只经组织病理学证实的CAA犬。在这个数据集中，CAA在成年大型犬中最常见的出现在嘴部下颌，金毛猎犬的比例过高。对治疗意向手术后有适当随访的患者进行评估，以评估组织病理切缘对局部肿瘤复发的影响。所有患者均未见局部复发。这项研究提出了一些问题，即治疗CAA的推荐手术范围应该是多少。这也是一个讨论的刺激，当手术切缘不足时，是否需要对CAA进行进一步治疗，或者医学监测是否将是一个适当的管理建议。为了回答这些问题，有必要进行前瞻性研究。
Canine acanthomatous ameloblastoma (CAA) has been reported to be the most common odontogenic tumor in dogs. This retrospective study evaluated 263 dogs with histopathologically confirmed CAA. Within this data set, CAA presents most commonly in the rostral mandible in adult large breed dogs, with golden retriever dogs being overrepresented. Patients with appropriate follow-up after curative intent surgery were evaluated to assess the effect of histopathological margin on local tumor recurrence. No local recurrence was noted in any patient. This study raises questions about what the recommended surgical margin should be for treatment of CAA. It also serves as a stimulus for discussion as to whether further treatment for CAA is required when inadequate surgical margins are obtained, or if medical surveillance would be an appropriate management recommendation. Prospective studies are necessary to answer these questions.