Adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a narrative review of the literature.
Adherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a narrative review of the literature.
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DOI：
10.1097/nor.0b013e3181e5c2c9
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发表时间：
2010-07
期刊：
影响因子：
--
通讯作者：
Frazier SK
中科院分区：
文献类型：
--
作者：
Salt E;Frazier SK
本文综合了类风湿性关节炎 (RA) 人群中疾病缓解抗风湿药物 (DMARD) 用药依从性的现有研究结果。本次文献综述包括 35 篇文章。 DMARD 的药物依从性范围为 30% 至 107%。坚持率大于 100% 表明患者服用的药物超过了处方量。没有发现一致的不遵守 DMARD 处方的危险因素，但提供了一些证据表明自我效能、患者与医疗保健提供者关系、社会支持、患者对药物的信念和年龄是影响药物依从性的因素。对以药物依从性为重点的教育干预措施的支持是模棱两可的。需要进一步的研究来对 RA 患者的药物依从性形成全面的、基于理论的理解。
This paper synthesizes findings from available research about medication adherence to disease modifying anti-rheumatic drugs (DMARDs) in the rheumatoid arthritis (RA) population. This review of literature included 35 articles. Medication adherence to DMARDs ranged from 30% to 107%. Adherence rates greater than 100% indicated that patients took more than the prescribed amount of medication. There were no consistent risk factors for nonadherence to DMARD prescriptions identified, but some evidence was provided for self-efficacy, patient-health care provider relationships, social support, patient beliefs about medications, and age as factors affecting medication adherence. Support for educational interventions focused on medication adherence was equivocal. Further research is necessary to develop a comprehensive, theoretically-based understanding of medication adherence in RA patients.