Responses of Neurons in Chinchilla Auditory Cortex to Frequency-Modulated Tones

Responses of Neurons in Chinchilla Auditory Cortex to Frequency-Modulated Tones
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DOI:
10.1152/jn.90931.2008
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发表时间:
2009-04-01
影响因子:
2.5
通讯作者:
Harrison, Robert V.
Harrison, Robert V.
中科院分区:
医学3区
文献类型:
--
作者:
Brown, Trecia A.;Harrison, Robert V.

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布朗助教哈里森房车毛丝鼠听皮层神经元对调频音调的反应。神经生理学杂志101:2017-2029,2009。首次发表于2009年2月11日; doi:10.1152/jn.90931.2008。调频(FM)刺激已被用于探索几种动物模型的听觉皮层神经元的行为,然而,在灰鼠FM敏感的听觉皮层神经元的属性仍然是未知的。从麻醉的成年灰鼠(Chinchilla laniger)的听觉皮层获得对FM刺激的单单位反应。向上和向下的线性FM扫描频率从0.1到20 kHz,以0.05到0.82 kHz/ms的速度。结果表明,>90%的采样神经元对FM扫描有反应。人口的偏好是向上调频扫描和中速到快速(>= 0.3 kHz/ms)。很少有单位(3%)选择向下调频扫描,而
Brown TA, Harrison RV. Responses of neurons in chinchilla auditory cortex to frequency-modulated tones. J Neurophysiol 101: 2017-2029, 2009. First published February 11, 2009; doi:10.1152/jn.90931.2008. Frequency-modulated ( FM) stimuli have been used to explore the behavior of neurons in the auditory cortex of several animal models; however, the properties of FM-sensitive auditory cortical neurons in the chinchilla are still unknown. Single-unit responses to FM stimulation were obtained from the auditory cortex of anesthetized adult chinchillas ( Chinchilla laniger). Upward and downward linear FM sweeps spanning frequencies from 0.1 to 20 kHz were presented at speeds of 0.05 to 0.82 kHz/ms. Results indicated that >90% of sampled neurons were responsive to FM sweeps. The population preference was for upward FM sweeps and for medium to fast speeds (>= 0.3 kHz/ms). Few units (3%) were selective for downward FM sweeps, whereas