Effect of a short-term exercise program on glycemic control measured by fructosamine test in type 2 diabetes patients
Effect of a short-term exercise program on glycemic control measured by fructosamine test in type 2 diabetes patients
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短期运动计划对 2 型糖尿病患者果糖胺测试血糖控制的影响
DOI：
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发表时间：
2014
影响因子：
4.8
通讯作者：
J. Marins
中科院分区：
文献类型：
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作者：
B. Moura;Paulo Amorim;Bruno PP Silva;S. C. Franceschini;J. Reis;J. Marins
背景糖化血红蛋白（A1 C）和空腹血糖（FPG）是最常用的两种血糖监测方法。然而，这两种方法被证明是不敏感的检测血糖变化在短时间内。因此，我们的目的是评估短期运动计划对血糖水平测定果糖胺浓度在2型diabetespatient.MethodsEight志愿者（51.1 ± 8.2岁）进行了监督运动计划在8周（3天。周-1，50-60%的VO 2峰值为30-60分钟）。观察体成分、VO 2峰值、A1 C、FPG、果糖胺和毛细血管血糖（CBG）。我们使用ANOVA -单向重复测量，然后进行Tukey事后检验和配对t检验。结果果糖胺、VO 2峰值、CBG浓度与对照组比较差异有统计学意义。而A1 C和FPG无统计学差异。从研究开始到研究结束，果糖胺下降了15%（57 μmol/L）。单独地，50%的样品达到果糖胺试验正态性的参考值。VO 2峰值增加了14.8%（3.8 ml·kg-1·min-1），CBG平均下降了34.4%（69.3 mg/dL）。结论果糖胺试验是有效的评估血糖与2型糖尿病患者进行短期运动计划时，替代传统的A1 C和FPG评估。我们的研究结果在临床实践中是相关的，因为血糖状态的显着改善可以帮助评估纳入运动作为辅助治疗，以取代处方的其他药物控制不佳的患者。
BackgroundGlycated hemoglobin (A1C) and Fasting Plasma Glucose (FPG) are the two monitoring blood glucose tests most frequently used. However, both methods are shown to be insensitive to detect glycemic variations in short duration periods. Therefore, we aimed to assess the effect of a short-term exercise program on glycemic levels measured by fructosamine concentrations in type 2 diabetes patients.MethodsEight volunteers (51.1 ± 8.2 years) underwent a supervised exercise program during eight weeks (3 d.wk-1, 50-60% of VO2 peak for 30–60 minutes). The body composition, VO2 peak, A1C, FPG, fructosamine and capillary blood glucose (CBG) were evaluated. We used ANOVA - One Way for repeated measures followed by Tukey post-hoc test and paired t test. P values <0.05 were considered significant.ResultsWe found statistical differences on the concentrations of fructosamine, VO2 peak and CBG. However, A1C and FPG showed no statistical difference. Fructosamine declined by 15% (57 μmol/L) between the beginning and the end of the study. Individually, 50% of the sample reached the reference values for the normality in fructosamine test. VO2 peak increased by 14.8% (3.8 ml.kg-1.min-1) and CBG decreased on an average of 34.4% (69.3 mg/dL).ConclusionsFructosamine test is effective in the evaluation of glucose with type 2 diabetes patients when undergoing a short exercise program, alternatively to the traditional A1C and FPG assessment. Our results are relevant in clinical practice, because the significant improvement in glycemic status can help to evaluate the inclusion of exercise as adjunct therapy to replace the prescription of additional drugs in poorly controlled patients.
DOI：
10.1016/s0735-1097(00)01054-8
发表时间：
2001-01-01
影响因子：
24
作者：
Tanaka, H;Monahan, KD;Seals, DR
通讯作者：
Seals, DR