Honeycomb-Patterned Films Fabricated by Self-Organization of DNA-Surfactant Complexes
Honeycomb-Patterned Films Fabricated by Self-Organization of DNA-Surfactant Complexes
复制标题
DNA-表面活性剂复合物自组织制备蜂窝状薄膜
DOI：
10.1021/la900322d
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发表时间：
2009-09-15
期刊：
影响因子：
3.9
通讯作者：
Wu, Lixin
中科院分区：
文献类型：
--
作者：
Sun, Hang;Li, Wen;Wu, Lixin
本文采用简单的溶液浇铸工艺，在高相对湿度条件下，用阳离子表面活性剂二烷基二甲基铵（DTDA）包封DNA，成功构建了基于DNA的蜂窝膜。在DNA- dtda复合物中，阳离子表面活性剂以1:1的摩尔比静电吸附在DNA的磷酸阴离子上。研究了底物、浓度和溶剂对微孔膜形态的影响，证明了DNA-DTDA自组织微孔膜形成的广泛性和高重复性。微孔结构的形态可以通过稍微改变复合溶液的浓度来调节。经圆二色性光谱证实，DNA以双螺旋B型存在于微孔膜中，染料分子罗丹明B被加载到DNA- dtda复合物中，形成荧光微孔膜。DNA-DTDA配合物作为宿主材料为荧光微孔膜的制备提供了一种新的方法。基于dna的有序蜂窝膜在光学和光电子器件、分离、离子传输和生物传感器等方面具有广泛的应用前景。
In this paper, DNA-based honeycomb films were successfully constructed from a simple solution casting process at high relative humidity, through the encapsulation of DNA with a cationic surfactant ditetradecyldimethylammonium (DTDA). Cationic surfactants electrostatically attach to phosphate anions of DNA in a molar ratio of 1:1 in the DNA-DTDA complex. Investigation of the effects of substrate, concentration, and solvent on the morphology of the microporous films demonstrated the wide generality and high reproducibility of the formation of DNA-DTDA self-organized microporous films. The morphology of the microporous structures can be adjusted by slightly changing the concentration of the complex solution. DNA exists in the double helical B-form in the microporous film confirmed by circular dichroism spectrum, Dye molecule rhodamine B was loaded into the DNA-DTDA complex, presenting a fluorescent microporous film. DNA-DTDA complex as a host material provides a new method for tailoring fluorescent microporous Films. The DNA-based ordered honeycomb films should be attractive for use in optical and optoelectronic devices, separation, ion transportation, and biosensors.