Evidence of antibodies against SARS-CoV-2 in wild mustelids from Brittany (France)
Evidence of antibodies against SARS-CoV-2 in wild mustelids from Brittany (France)
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DOI：
10.1111/tbed.14663
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发表时间：
2022-07-27
影响因子：
4.3
通讯作者：
Edouard, Sophie
中科院分区：
文献类型：
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作者：
Davoust, Bernard;Guerin, Patrick;Edouard, Sophie
在法国布列塔尼地区，主要是在Cotes d 'Armor省，2021年上半年，在33只受试动物中，有5只野生鼬科动物（15. 6%）检测到SARS-CoV-2血清阳性。用免疫印迹法检测了3只松貂和2只獾的SARS-CoV-2 IgG抗体。ELISA检测也发现了血清阳性病例，尽管这些与蛋白质印迹结果不一致。尽管对33只鼬科动物的样本进行的171次qPCR均为阴性，但这项观察性研究的初步结果仍然证明了来源不明的感染。必须继续对野生动物中的新冠肺炎进行流行病学监测，特别是使用有效的血清学工具。
In the French region of Brittany, mainly in the department of the Cotes d'Armor, during the first half of 2021, seropositivity for SARS-CoV-2 was detected in five wild mustelids out of 33 animals tested (15.6%). Anti-SARS-CoV-2 IgG was detected against at least four out of five recombinant viral proteins (S1 receptor binding domain, nucleocapsid, S1 subunit, S2 subunit and spike) in three pine martens (Martes martes) and in two badgers (Meles meles) using the automated western blot technique. An ELISA test also identified seropositive cases, although these did not align with western blot results. Although the 171 qPCRs carried out on samples from the 33 mustelids were all negative, these preliminary results from this observational study nevertheless bear witness to infections of unknown origin. The epidemiological surveillance of Covid-19 in wildlife must continue, in particular with effective serology tools.