Lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect.

Lost in translation: ambiguity in nerve sheath tumor nomenclature and its resultant treatment effect.
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DOI:
10.3390/cancers5020519
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发表时间:
2013-05-08
期刊:
影响因子:
5.2
通讯作者:
Randall, R Lor
Randall, R Lor
中科院分区:
医学2区
文献类型:
--
作者:
Bernthal, Nicholas M;Jones, Kevin B;Randall, R Lor

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There is much ambiguity surrounding the diagnosis of nerve sheath tumors, including atypical neurofibroma and low-grade MPNST, and yet, the distinction between these entities designates either benign or malignant behavior and thus carries presumed profound prognostic importance that often guides treatment. This study reviews the diagnostic criteria used to designate atypical neurofibroma from low-grade MPNSTs and reviews existing literature the natural history of each of these tumors to see if the distinction is, in fact, of importance.