Enhanced forearm blood flow during mental stress in children of hypertensive parents.
Enhanced forearm blood flow during mental stress in children of hypertensive parents.
复制标题
高血压父母的孩子在精神压力期间前臂血流量增强。
DOI：
10.1161/01.hyp.10.5.544
复制
发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Clarke,WR
中科院分区：
文献类型：
--
作者：
Anderson,EA;Mahoney,LT;Lauer,RM;Clarke,WR
本研究比较了12名父母有高血压的青少年和13名父母血压正常的年龄匹配的青少年的前臂血流、前臂血管阻力、血压和心率的变化。两组在静息前臂血流量、前臂血管阻力、心率或血压方面没有差异。在精神压力期间，有高血压家族史的儿童前臂血流量的增加显著大于父母血压正常的儿童（+37.5 +/-8.0 vs +12.8 +/-7.5%; p <0.05），并有前臂血管阻力降低的趋势（p = 0.08）。精神压力显著增加了两组的收缩压（p <0.0001）、舒张压（p <0.001）和心率（p <0.03）。血压和心率对压力的反应在两组之间没有显著差异。在有高血压家族史的儿童中，没有证据表明有延长的反应或不同的恢复模式。这项研究表明，在精神压力下类似的血压升高的基础上的局部血流反应可能是不同的，在青少年有和没有高血压家族史。
This study compared changes in forearm blood flow, forearm vascular resistance, blood pressure, and heart rate elicited by mental stress (mental arithmetic) in 12 adolescents with a hypertensive parent and 13 age-matched adolescents with normotensive parents. The two groups did not differ in resting forearm blood flow, forearm vascular resistance, heart rate, or blood pressure. During mental stress, children with a family history of hypertension had a significantly greater increase in forearm blood flow than did children of normotensive parents (+37.5 +/- 8.0 vs +12.8 +/- 7.5%; p less than 0.05) and a trend toward reduced forearm vascular resistance (p = 0.08). Mental stress significantly increased systolic blood pressure (p less than 0.0001), diastolic blood pressure (p less than 0.001), and heart rate (p less than 0.03) in both groups. The blood pressure and heart rate responses to stress were not significantly different between groups. There was no evidence of a prolonged response or a different pattern of recovery in children with a family history of hypertension. This study indicates that regional blood flow responses underlying similar blood pressure increases during mental stress may be different in adolescents with and without a family history of hypertension.