Disseminated visceral giant cell arteritis: histopathologic description and differentiation from other granulomatous vasculitides.
Disseminated visceral giant cell arteritis: histopathologic description and differentiation from other granulomatous vasculitides.
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播散性内脏巨细胞动脉炎：组织病理学描述以及与其他肉芽肿性血管炎的区别。
DOI：
10.1093/ajcp/69.1.299
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发表时间：
1978
影响因子：
3.5
通讯作者：
J. Lie
中科院分区：
文献类型：
--
作者：
J. Lie
弥散性内脏巨细胞动脉炎，一个以前未知的实体，观察到四个尸检患者，所有男性，年龄33，67，59和45岁。所有患者均无颞动脉炎、胶原病、结节病、肝炎或其他感染，血管炎是在死亡后才诊断出来的。所有患者均患有以下器官中至少三个部位的颅外动脉和小动脉巨细胞动脉炎：心脏、肺、肾、肝、胰腺和胃。尽管有一些组织病理学相似性，但播散性内脏巨细胞动脉炎可通过主要受累血管的类型和巨细胞、血管纤维素样坏死和嗜酸性浸润的存在与否与其他坏死性和肉芽肿性血管炎区分开来。观察结果表明，这是一个独特的类型的系统性血管炎。
Disseminated visceral giant cell arteristic, a previously unknown entity, was observed in four autopsied patients, all men, aged 33, 67, 59 and 45 years. None of the patients had temporal arteritis, collagen disease, sarcoidosis, hepatitis or other infections, and vasculitis was diagnosed only after death. All had giant cell arteritis of extracranial arteries and arterioles in at least three of the following organs: the heart, lungs, kidneys, liver, pancreas, and stomach in various combinations. Despite some histopathologic similarities, disseminated visceral giant cell arteritis can be distinguished from other necrotizing and granulomatous vasculitides by the type of vessels principally affected and the presence or absence of giant cells, vascular fibrinoid necrosis and eosinophilic infiltrates. The observations suggest that it is a distinctive type of systemic vasculitis.