Glucose tolerance in Polynesia: association with obesity and island of residence.
Glucose tolerance in Polynesia: association with obesity and island of residence.
复制标题
波利尼西亚的葡萄糖耐量：与肥胖和居住岛的关系。
DOI：
10.1016/s0168-8227(88)80009-3
复制
发表时间：
1988
影响因子：
5.1
通讯作者：
Taylor,RJ
中科院分区：
文献类型：
--
作者：
King,H;Zimmet,PZ;Taylor,RJ
通过 1978 年至 1980 年期间进行的标准化人口调查获得了五个波利尼西亚人口的数据，检查了葡萄糖耐量与肥胖和居住岛之间的关联。在男女中，考虑到年龄和肥胖的影响后，主观上被认为不太传统的三个人口和被认为保留了更传统生活方式的两个人口之间的葡萄糖耐量存在显着差异。预测糖尿病状态的回归模型弱于使用葡萄糖耐量作为因变量的回归模型，这可能是由于样本中糖尿病受试者的数量较少。由于所有受试者都有波利尼西亚血统，并且结果无法通过五个人群之间的祖先关系知识来解释，环境因素而不是遗传因素可能是观察到的葡萄糖耐量差异的决定因素。这一发现凸显了需要采用更复杂的方法来研究太平洋地区社会文化现代化与慢性病之间的关系。
Data on five polynesian populations, obtained by standardized population surveys conducted during the years 1978–1980, were examined for associations between glucose tolerance and both obesity and island of residence.In both sexes, after allowing for the influence of age and obesity, there was a significant difference in glucose tolerance between the three populations considered, subjectively, to be the less traditional and the two considered as retaining a more traditional lifestyle. Regression models predicting diabetic status were weaker than those using glucose tolerance as the dependent variable, probably due to the small number of diabetic subjects in the samples.As all subjects were of Polynesian ancestry, and the results could not be explained by knowledge of ancestral affiliations between the five populations, environmental, rather than genetic factors may have been the determinants of the observed differences in glucose tolerance. This finding highlights the need for a more sophisticated approach to the study of the association between socio-cultural modernization and chronic disease in the Pacific.