BEHAVIOURAL EFFECTS OF LEVALLORPHAN, CYPRENORPHINE (M285) AND AMPHETAMINE ON REPEATED Y-MAZE PERFORMANCE IN RATS
BEHAVIOURAL EFFECTS OF LEVALLORPHAN, CYPRENORPHINE (M285) AND AMPHETAMINE ON REPEATED Y-MAZE PERFORMANCE IN RATS
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DOI：
10.1007/bf00403864
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发表时间：
1971-01-01
期刊：
影响因子：
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通讯作者：
COWAN, A
中科院分区：
文献类型：
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作者：
WRAY, SR;COWAN, A
研究了左洛啡烷和环丙诺啡（M285）对大鼠重复Y-迷宫行为的影响。据推测，这些麻醉剂拮抗剂-牵连作为拟精神病药物-会破坏经验的过程，并增加恐惧动机的行为。这些化合物对行为产生不同的影响。左丙诺啡诱导bizarphine兴奋和破坏习惯; cyprenorphine在这些方面无效。没有观察到恐惧动机行为的增加。安非他明增加自发活动，而不影响习惯。
The effects of levallorphan and cyprenorphine (M 285) were studied on repeated Y-maze performance in rats. It was postulated that these narcotic antagonists—implicated as psychotomimetics—would disrupt the experiencing process and augment fear-motivated behaviour. These compounds produced differential effects on behaviour. Levallorphan induced bizarre-excitation and disrupted habituation; cyprenorphine was ineffective in these respects. No augmentation of fear-motivated behaviour was observed. Amphetamine increased locomotor activity without affecting habituation.