Serum amyloid A as a prognostic marker in cats with various diseases
Serum amyloid A as a prognostic marker in cats with various diseases
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DOI：
10.1177/1040638713486112
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发表时间：
2013-05-01
影响因子：
1.5
通讯作者：
Tsujimoto, Hajime
中科院分区：
文献类型：
--
作者：
Tamamoto, Takashi;Ohno, Koichi;Tsujimoto, Hajime
据报道，血清淀粉样蛋白A （SAA）不仅是炎症存在的标志，而且是人类预后的指标。然而，在猫中，没有关于SAA浓度与预后之间关系的报道。本研究的目的是评估SAA浓度作为病猫的预后指标。研究人员回顾性地招募了175只患有肿瘤性疾病、炎症性疾病和其他疾病的猫，并回顾了这些猫的医疗记录，包括死亡率的随访数据。根据SAA浓度将猫分为2组，评估各组猫的生存差异。SAA （> 0.82 mg/l）升高组猫的中位生存时间显著短于SAA（货币）未升高组
Serum amyloid A (SAA) is reported not only as a marker for the presence of inflammation but also as a prognostic indicator in human beings. In cats, however, there is no report on the association between SAA concentration and prognosis. The objective of the current study was to evaluate SAA concentration as a prognostic marker in diseased cats. A total of 175 cats with neoplastic diseases, inflammatory diseases, and other diseases were retrospectively recruited, and the medical records of these cats, including follow-up data on mortality, were reviewed. Cats were divided into 2 groups according to SAA concentration, and differences in survival between each group were assessed. Median survival time of cats in the elevated SAA (> 0.82 mg/l) group was significantly shorter than that in the nonelevated SAA (acurrency