The roles of CD147 and/or cyclophilin A in kidney diseases.
The roles of CD147 and/or cyclophilin A in kidney diseases.
复制标题
CD147 和/或亲环蛋白 A 在肾脏疾病中的作用
DOI:
10.1155/2014/728673
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发表时间:
2014
影响因子:
4.6
通讯作者:
Zhou J
中科院分区:
文献类型:
--
作者:
Qu X;Wang C;Zhang J;Qie G;Zhou J
CD147 is a widely expressed integral plasma membrane glycoprotein and has been involved in a variety of physiological and pathological activities in combination with different partners, including cyclophilins, caveolin-1, monocarboxylate transporters, and integrins. Recent data demonstrate that both CyPA and CD147 significantly contribute to renal inflammation, acute kidney injury, renal fibrosis, and renal cell carcinoma. Here we review the current understanding of cyclophilin A and CD147 expression and functions in kidney diseases and potential implications for treatment of kidney diseases.
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影响因子:
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作者:
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通讯作者:
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