Significance of palliative gastrectomy for late-stage gastric cancer patients
Significance of palliative gastrectomy for late-stage gastric cancer patients
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DOI：
10.1002/jso.23158
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发表时间：
2012-12-01
影响因子：
2.5
通讯作者：
Chen, Ying-Bo
中科院分区：
文献类型：
--
作者：
Chen, Shi;Li, Yuan-Fang;Chen, Ying-Bo
目的：探讨姑息性胃切除术对不同类型的转移性胃癌患者的意义，包括腹膜转移、肝转移、晚期局部发生的远处淋巴结转移以及多器官转移。我们对862例在中山医院经组织学诊断为晚期胃癌，无法接受根治性手术的患者进行了回顾性研究。1993年1月至2008年12月，森大学癌症中心。随访持续到2010年12月。结果：在腹腔播散组和多器官转移组中，姑息性胃切除术对生存率无明显影响（P = 0.05）。0.705，0.331）。在远处淋巴结转移、肝转移和局部晚期胃癌患者中，姑息性胃切除术是预后因素（P？
Purpose: To investigate the significance of palliative gastrectomy for different types of metastatic gastric cancer patients displaying peritoneal dissemination, hepatic metastasis, distant lymph node metastasis occurring locally during late-stage disease, and multi-organ metastases.Methods: We performed a retrospective study of 862 patients who were histologically diagnosed as late-stage gastric cancer who could not undergo radical surgery at the Sun Yat-sen University Cancer Center between January 1993 and December 2008. The follow-up lasted until December 2010. Chi-square tests and KaplanMeier methods were employed to compare the adverse events and prognoses.Results: In the peritoneal dissemination and multi-organ metastases groups, palliative gastrectomy has no survival benefit (P?=?0.705, 0.331, respectively). In the patients with distant lymph-node metastases, liver metastasis and locally late-stage gastric cancer patients, palliative gastrectomy was a prognostic factor (P?