Occult radiopaque jaw lesions in familial adenomatous polyposis coli and hereditary nonpolyposis colorectal cancer.

Occult radiopaque jaw lesions in familial adenomatous polyposis coli and hereditary nonpolyposis colorectal cancer.
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家族性腺瘤性大肠杆菌和遗传性非息肉性结直肠癌的隐匿性不透射线颌部病变。

DOI:
10.1016/0016-5085(87)90910-3
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发表时间:
1987
期刊:
影响因子:
29.4
通讯作者:
Hamilton,SR
Hamilton,SR
中科院分区:
医学1区
文献类型:
--
作者:
Offerhaus,GJ;Levin,LS;Giardiello,FM;Krush,AJ;Welsh,SB;Booker,SV;Hasler,JF;McKusick,VA;Yardley,JH;Hamilton,SR

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The purposes of this study were to determine the association, in 10 pedigrees, between adenomatous polyposis coli, hereditary nonpolyposis colorectal cancer, and occult radiopaque jaw lesions, and to assess whether these radiodensities are predictors for adenomatous polyposis. In seven kindreds with adenomatous polyposis, all patients with polyps had jaw lesions; in one kindred, no jaw lesions were found. In one of two kindreds with hereditary nonpolyposis colorectal cancer, no affected individuals had jaw lesions. In the other, the 1 affected patient with dental radiographs had generalized jaw lesions. Twelve children <16 yr old at risk for adenomatous polyposis were observed. Seven children with jaw lesions developed polyps afer a mean interval of 4 yr. Five children without jaw lesions were polyp-free during a 5–10-yr follow-up. Thus, occult jaw lesions are consistently found only in some families with adenomatous polyposis coli, providing support for heterogeneity in polyposis syndromes. Jaw lesions are good predictors for polyp development in kindreds with adenomatous polyposis coli and jaw lesions. Their role as markers in hereditary nonpolyposis colorectal cancer needs exploration.
DOI: --
发表时间: 1979
期刊: Oral surgery, oral medicine, and oral pathology
影响因子: --
作者:
G. Ritchie;A. M. Fletcher
通讯作者: A. M. Fletcher
DOI: --
发表时间: 1986
期刊: Gastroenterology
影响因子: 29.4
作者:
J. Mecklin;H. Järvinen;P. Peltokallio
通讯作者: P. Peltokallio
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DOI: --
发表时间: 1982
影响因子: 4
作者:
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DOI: 10.1002/ajmg.1320210207
发表时间: 1985
期刊: American journal of medical genetics
影响因子: --
作者:
Levin,LS;Wright,JM;Byrd,DL;Greenway,G;Dorst,JP;Irani,RN;Pyeritz,RE;Young,RJ;Laspia,CL
通讯作者: Laspia,CL
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DOI: --
发表时间: 1978
期刊:
影响因子: --
作者:
Rabinovich Ms;P. Hi
通讯作者: P. Hi