Chronic and acute stress as predictors of relapse in primary breast cancer patients
Chronic and acute stress as predictors of relapse in primary breast cancer patients
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DOI：
10.1016/s0738-3991(99)00030-0
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发表时间：
1999-07-01
影响因子：
3.5
通讯作者：
Gerits, P
中科院分区：
文献类型：
--
作者：
De Brabander, B;Gerits, P
在本文中，我们介绍了44例原发性乳腺癌患者早期复发（术后三年半）的预测数据。我们预计，接受恶性肿瘤诊断的程度将作为一个急性应激源，将允许早期复发的预测。急性应激是通过诊断交流前后应激的心理、神经化学和免疫学指标的变化来测量的。结果表明，这种假设并不成立，然而，慢性压力似乎是早期复发的一个强有力的预测因素。慢性压力的测量是根据乳腺癌诊断前一年健康投诉的自我报告问卷。1999爱思唯尔科学爱尔兰有限公司版权所有。
In this paper we present data on predictors of early relapse (at three and a half years post-surgery) in 44 patients with primary breast carcinoma. We expected that the degree to which receiving the diagnosis of malignancy would act as an acute stressor would allow a prediction of early relapse. Acute stress is measured by means of changes in psychological, neurochemical and immunological indicators of stress before and after the communication of the diagnosis. The results indicate that the assumption does not hold, Chronic stress, however, appears to be a strong predictor of early relapse. The measure of chronic stress is based on a self-report questionnaire of health complaints in the year before the diagnosis of breast cancer. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.