Editorial: Podocytes as Active Participants in Lupus Nephritis.

Editorial: Podocytes as Active Participants in Lupus Nephritis.
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社论:足细胞是狼疮性肾炎的积极参与者。

DOI:
10.1002/art.40157
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发表时间:
2017
期刊:
Arthritis & rheumatology (Hoboken, N.J.)
影响因子:
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通讯作者:
Bonegio,RamonG
Bonegio,RamonG
中科院分区:
--
文献类型:
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作者:
Rifkin,IanR;Bonegio,RamonG

文献摘要

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本文介绍足细胞及其与狼疮性肾炎的关系。足细胞是围绕肾小球毛细血管袢的高度分化的上皮细胞。最近的研究并没有证实足细胞在局灶性和节段性肾小球硬化或狼疮性肾炎患者中的表达。傅教授对人狼疮性肾炎期间肾小球足细胞炎性小体活化的研究也进行了探讨。
The article offers information on podocytes and their relation with lupus nephritis. Podocytes are much differentiated epithelial cells which surround glomerular capillary loops. Recent studies did not confirm expression on podocytes in relatively big cohorts of patients with focal and segmental glomerular sclerosis or lupus nephritis. A study by R. Fu on activation of inflammasome in glomerular podocytes during human lupus nephritis is also examined.