Chronicles of the GTPase switch
Chronicles of the GTPase switch
复制标题
DOI:
10.1038/nchembio.608
复制
发表时间:
2011-08-01
影响因子:
14.8
通讯作者:
Zeghouf, Mahel
中科院分区:
文献类型:
--
作者:
Cherfils, Jacqueline;Zeghouf, Mahel
The GTPase switch is a versatile molecular device used by many proteins, such as the small GTPases, to regulate an astounding number of functions. Although the basics of the guanine nucleotide cycle are now well established, the next challenge is to reach an integrated view of how these proteins use it to orchestrate signaling pathways.