Racial/Ethnic and Gender Disparities in Heart Failure with Reduced Ejection Fraction.

Racial/Ethnic and Gender Disparities in Heart Failure with Reduced Ejection Fraction.
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DOI:
10.1007/s11897-021-00502-5
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发表时间:
2021-04
影响因子:
--
通讯作者:
Breathett K
Breathett K
中科院分区:
其他
文献类型:
--
作者:
Mwansa H;Lewsey S;Mazimba S;Breathett K

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本综述强调了非药物性心力衰竭降低射血分数(HFrEF)治疗处方因种族、民族和性别而异。审查还探讨了这些不平等现象背后的证据以及可能的缓解战略。心衰治疗取得了重大进展,提高了心衰患者的总生存率。然而,有色人种和女性并没有获得公平的治疗机会。有色人种和女性患者接受非药物治疗HFrEF的可能性低于白人和男性。包括运动康复、经皮经导管二尖瓣修复、心脏再同步化治疗、心脏移植和心室辅助装置在内的治疗方法都已被证明对有色人种和女性患者有效,但处方仍然不足。大多数非药物治疗的结果在有色人种和女性患者中与白人和男性患者相似或更好。迫切需要系统层面的改革,以实现按种族、民族和性别公平获得非药物HFrEF治疗。
This review highlights variability in prescribing of non-pharmacologic heart failure with reduced ejection fraction (HFrEF) therapies by race, ethnicity, and gender. The review also explores the evidence underlying these inequalities as well as potential mitigation strategies. There have been major advances in HF therapies that have led to improved overall survival of HF patients. However, racial, and ethnic groups of color and women have not received equitable access to these therapies. Patients of color and women are less likely to receive non-pharmacologic therapies for HFrEF than Whites and men. Therapies including exercise rehabilitation, percutaneous transcatheter mitral valve repair, cardiac resynchronization therapy, heart transplant, and ventricular assist devices all have proven efficacy in patients of color and women but remain under-prescribed. Outcomes with most non-pharmacologic therapy are similar or better among patients of color and women than White patients and men. System-level changes are urgently needed to achieve equity in access to non-pharmacologic HFrEF therapies by race, ethnicity, and gender.
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