Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin.
Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin.
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DOI：
10.5650/jos.56.615
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发表时间：
2007
影响因子：
1.5
通讯作者：
Hayato Maeda;M. Hosokawa;Tokutake Sashima;Katsura Funayama;K. Miyashita
中科院分区：
文献类型：
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作者：
Hayato Maeda;M. Hosokawa;Tokutake Sashima;Katsura Funayama;K. Miyashita
以KK-Ay肥胖小鼠为模型，研究了中链三酰甘油(MCT)和岩藻黄质(FC)对小鼠腹脂重量的影响。试验日粮含MCT(0.9%)、FC(0.1%)或MCT(0.9%)+FC(0.1%)。饲喂FC的小鼠腹脂重量显著低于饲喂MCT的小鼠。解偶联蛋白1(UCP1)是代谢产热的关键分子，在饲喂FC的小鼠白色脂肪组织(WAT)中有明显的表达，而在饲喂MCT的小鼠的白色脂肪组织中几乎没有表达。FC与MCT混合使用，可提高FC的减肥效果。这一增长将是由于MCT增加了FC的吸收率。
Dietary effects of medium-chain triacylglycerols (MCT) and fucoxanthin (Fc) on abdominal fat weight were determined using KK-Ay obese mouse. Experimental diet contained MCT(0.9%), Fc (0.1%), or MCT (0.9%) +Fc (0.1%). The abdominal fat weight of mice fed with Fc was significantly lower than that of mice fed with MCT. Uncoupling protein 1 (UCP1), a key molecule for metabolic thermogenesis, was clearly expressed in the white adipose tissue (WAT) of mice fed Fc, but little expression in that of the mice fed MCT. The anti-obesity effect of Fc was increased by mixing Fc with MCT. This increase would be due to the increase in the absorption rate of Fc by MCT.