Compliance with and effectiveness of adaptive servoventilation versus continuous positive airway pressure in the treatment of Cheyne-Stokes respiration in heart failure over a six month period
Compliance with and effectiveness of adaptive servoventilation versus continuous positive airway pressure in the treatment of Cheyne-Stokes respiration in heart failure over a six month period
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DOI：
10.1136/hrt.2005.060038
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发表时间：
2006-03-01
期刊：
影响因子：
5.7
通讯作者：
d'Ortho, MP
中科院分区：
文献类型：
--
作者：
Philippe, C;Stoïca-Herman, M;d'Ortho, MP
目的：比较适应性伺服通气（ASV）与持续气道正压通气（CPAP）在伴有Cheyne-Stokes呼吸（CSR）的中枢性睡眠呼吸暂停综合征（CSA）和充血性心力衰竭患者中的依从性和有效性，包括6个月的呼吸暂停-低通气指数（AHI）、生活质量和左心室射血分数（LVEF）。25例患有稳定充血性心力衰竭和CSA-CSR的患者（年龄28 - 80岁，纽约心脏协会（NYHA）II - IV级）被随机分配至CPAP或ASV组。入选时，两组的NYHA分级，LVEF，药物治疗，体重指数，和CSA-CSR。结果：ASV和CPAP都降低了AHI，但值得注意的是，只有ASV完全纠正CSA-CSR，AHI低于10/h。在3个月时，ASV和CPAP之间的依从性相当;然而，在6个月时，CPAP的依从性显著低于ASV。在6个月，生活质量的改善是更高的ASV和只有ASV引起了显着增加LVEF.Conclusion：这些结果表明，CSA-CSR患者可能会收到更大的好处，从治疗ASV比CPAP。
Objective: To compare compliance with and effectiveness of adaptive servoventilation (ASV) versus continuous positive airway pressure ( CPAP) in patients with the central sleep apnoea syndrome (CSA) with Cheyne-Stokes respiration (CSR) and with congestive heart failure in terms of the apnoea - hypopnoea index (AHI), quality of life, and left ventricular ejection fraction (LVEF) over six months.Methods: 25 patients ( age 28 - 80 years, New York Heart Association (NYHA) class II - IV) with stable congestive heart failure and CSA-CSR were randomly assigned to either CPAP or ASV. At inclusion, both groups were comparable for NYHA class, LVEF, medical treatment, body mass index, and CSA-CSR.Results: Both ASV and CPAP decreased the AHI but, noticeably, only ASV completely corrected CSA-CSR, with AHI below 10/h. At three months, compliance was comparable between ASV and CPAP; however, at six months compliance with CPAP was significantly less than with ASV. At six months, the improvement in quality of life was higher with ASV and only ASV induced a significant increase in LVEF.Conclusion: These results suggest that patients with CSA-CSR may receive greater benefit from treatment with ASV than with CPAP.