Comparisons of prevalence and related factors of depression in middle-aged adults between urban and rural populations in Japan
Comparisons of prevalence and related factors of depression in middle-aged adults between urban and rural populations in Japan
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DOI：
10.1016/j.jad.2015.11.020
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发表时间：
2016-01-15
影响因子：
6.6
通讯作者：
Ikeda, Manabu
中科院分区：
文献类型：
--
作者：
Fujise, Noboru;Abe, Yasuhisa;Ikeda, Manabu
背景：城乡抑郁症患病率差异的研究结果一直存在争议，很少有报道直接比较城乡抑郁症的相关因素。本研究旨在调查日本城市和农村地区中年人抑郁症患病率及相关因素的差异，以进一步了解这一人群的抑郁症特征。方法：采用多阶段随机抽样和邮寄方法。共有5000名参与者从熊本县的城市和农村地区招募（每个地区2500人）。参与者的年龄从40岁到64岁不等。使用流行病学研究中心抑郁量表（CES-D）评估抑郁症。结果：城乡中年人抑郁症患病率无显著差异。Logistic回归分析发现，女性、独居和患有慢性疾病与城市中年人的抑郁显著相关。在城市和农村地区，年龄较小、睡眠障碍和经济压力与抑郁症显著相关。局限性：抑郁症的定义是基于CES-D评分，没有确凿的临床评价。结论：我们发现中年抑郁症的患病率在城市和农村地区没有显著差异。日本城市和农村地区中年人抑郁的相关因素存在差异。针对中年抑郁症患者的有效干预方案应考虑地区差异。(C) 2015 Elsevier B.V.版权所有
Background: Findings of urban-rural differences in the prevalence of depression have been controversial, and few reports have directly compared the related factors of depression between urban and rural areas. The present study aimed to investigate differences between urban and rural areas in Japan with regards to the prevalence of and related factors of depression in middle-aged adults, in order to further understanding of the features of depression in this demographic.Methods: We used a multistage, random sampling procedure and mailing method. In total, 5000 participants were recruited from urban and rural areas in Kumamoto Prefecture (2500 in each area). Participants were aged from 40 to 64 years. Depression was assessed using the Center for Epidemiologic Studies Depression scale (CES-D).Results: The prevalence of middle-aged depression was not different between the urban and rural areas. Logistic regression analysis found that being female, living alone, and having a chronic illness were significantly associated with depression in urban-dwelling middle-aged adults. Younger age, sleep disturbance, and financial strain were significantly associated with depression in both urban and rural areas.Limitations: The definition of depression was based on CES-D scores, without corroborating clinical evaluation.Conclusions: We found no marked differences in the prevalence of middle-aged depression between the urban and rural areas. Some related factors of depression in middle-aged adults differed between urban and rural areas in Japan. Effective intervention programs for middle-aged adults with depression should consider regional differences. (C) 2015 Elsevier B.V. All rights reserved.