Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge breakfasts: a randomised, crossover trial in healthy humans
Glycaemic, gastrointestinal, hormonal and appetitive responses to pearl millet or oats porridge breakfasts: a randomised, crossover trial in healthy humans
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DOI：
10.1017/s0007114519001880
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发表时间：
2019-11-28
影响因子：
3.6
通讯作者：
Marciani, Luca
中科院分区：
文献类型：
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作者：
Alyami, Jaber;Whitehouse, Ella;Marciani, Luca
全谷谷物早餐消费与葡萄糖和胰岛素代谢以及饱腹感的有益影响有关。珍珠粟是一种受欢迎的古老谷物品种，可以在炎热干燥的地区种植。然而，人们对其健康影响知之甚少。本研究调查了珍珠小米粥（PMP）与著名的苏格兰燕麦粥（SOP）对血液，胃肠道，激素和食欲反应的影响。在一项随机、双向交叉试验中，26名健康参与者食用了两份等能量/等体积PMP或SOP早餐，并喝了一杯水。餐后2 h采集血糖、胰岛素、胰高血糖素样肽1、葡萄糖依赖性促胰岛素多肽（GIP）、肽YY、胃容量和食欲评级的血样，然后随意进餐并记录当天剩余时间的摄食量。两种粥之间血糖的增量AUC（iAUC 2 h）无显著差异（P > 0，中心点05）。PMP的胃容量iAUC 2 h大于SOP（P = 0，中心点045）。PMP的GIP浓度的iAUC 2 h显著低于SOP（P = 0，中心点001）。其他激素和食欲反应在两餐之间是相似的。总之，本研究首次报告了珍珠小米早餐的血液和生理反应数据，表明这种古老的谷物可以代表一种可持续的替代品，具有与燕麦相当的健康促进特性。GIP是一种与脂肪组织中TAG吸收相关的肠促胰岛素激素;因此，PMP的较低GIP反应可能是一种额外的健康益处。
Whole-grain cereal breakfast consumption has been associated with beneficial effects on glucose and insulin metabolism as well as satiety. Pearl millet is a popular ancient grain variety that can be grown in hot, dry regions. However, little is known about its health effects. The present study investigated the effect of a pearl millet porridge (PMP) compared with a well-known Scottish oats porridge (SOP) on glycaemic, gastrointestinal, hormonal and appetitive responses. In a randomised, two-way crossover trial, twenty-six healthy participants consumed two isoenergetic/isovolumetric PMP or SOP breakfast meals, served with a drink of water. Blood samples for glucose, insulin, glucagon-like peptide 1, glucose-dependent insulinotropic polypeptide (GIP), peptide YY, gastric volumes and appetite ratings were collected 2 h postprandially, followed by an ad libitum meal and food intake records for the remainder of the day. The incremental AUC (iAUC2h) for blood glucose was not significantly different between the porridges (P > 0 center dot 05). The iAUC2h for gastric volume was larger for PMP compared with SOP (P = 0 center dot 045). The iAUC2h for GIP concentration was significantly lower for PMP compared with SOP (P = 0 center dot 001). Other hormones and appetite responses were similar between meals. In conclusion, the present study reports, for the first time, data on glycaemic and physiological responses to a pearl millet breakfast, showing that this ancient grain could represent a sustainable alternative with health-promoting characteristics comparable with oats. GIP is an incretin hormone linked to TAG absorption in adipose tissue; therefore, the lower GIP response for PMP may be an added health benefit.