Bilateral neurotoxic amygdala lesions in rhesus monkeys (Macaca mulatta):: Consistent pattern of behavior across different social contexts
Bilateral neurotoxic amygdala lesions in rhesus monkeys (Macaca mulatta):: Consistent pattern of behavior across different social contexts
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DOI：
10.1037/0735-7044.122.2.251
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发表时间：
2008-04-01
影响因子：
1.9
通讯作者：
Amaral, David G.
中科院分区：
文献类型：
--
作者：
Machado, Christopher J.;Emery, Nathan J.;Amaral, David G.
虽然杏仁核已被反复牵连在正常的灵长类动物的社会行为，很大的差异存在于特定的社会和非社会行为的变化，观察到非人类灵长类动物的双侧杏仁核病变。一个合理的解释与社会背景的差异有关。本研究测量了杏仁核损伤和未手术的恒河猴（Macaca mulatta）在2种情况下的社会行为。猴子在32个测试日内在4人社会群体中互动。他们以前被成对评估（N。J. Emery等人，2001年），因此在本研究开始时彼此熟悉。在这两种情况下，杏仁核损伤产生了高度一致的社会行为模式。与对照组相比，手术组猴子与对照组伙伴进行了更多的亲和性社会互动。在他们的互动过程中，杏仁核损伤的猴子也显示出比对照组更早的神经和恐惧的个性品质下降。杏仁核损毁的猴子成对的探索和性行为的增加在4人组中没有发现。作者得出结论，杏仁核有助于社会抑制，并且这种功能超越了各种社会背景。
Although the amygdala has been repeatedly implicated in normal primate social behavior, great variability exists in the specific social and nonsocial behavioral changes observed in nonhuman primates with bilateral amygdala lesions. One plausible explanation pertains to differences in social context. This study measured the social behavior of amygdala-lesioned and unoperated rhesus monkeys (Macaca mulatta) in 2 contexts. Monkeys interacted in 4-member social groups over 32 test days. They were previously assessed in pairs (N. J. Emery et al., 2001) and were therefore familiar with each other at the beginning of this study. Across the 2 contexts, amygdala lesions produced a highly consistent pattern of social behavior. Operated monkeys engaged in more affiliative social interactions with control partners than did controls. In the course of their interactions, amygdala-lesioned monkeys also displayed an earlier decrease in nervous and fearful personality qualities than did controls. The increased exploration and sexual behavior recorded for amygdala-lesioned monkeys in pairs was not found in the 4-member groups. The authors concluded that the amygdala contributes to social inhibition and that this function transcends various social contexts.