Evaluation of angiogenesis in chronic inflammation by laser-Doppler flowmetry.
Evaluation of angiogenesis in chronic inflammation by laser-Doppler flowmetry.
复制标题
通过激光多普勒血流计评估慢性炎症中的血管生成。
作者：
C. Orlandi;C. J. Dunn;L. Cutshaw
1.一种非侵入性的方法，用于评估血管生成的慢性炎症使用激光多普勒血流仪。2.与对照皮肤相比，在诱导皮下肉芽肿性病变后第5天和第7天观察到毛细血管血流量显著增加。3.血流的变化伴随着脉动流模式的变化，并通过光学显微镜观察到强烈的血管生成反应。4.潜在的应用激光多普勒血流定量和定性研究不断发展的血管生成的病理反应进行了讨论。
1. A non-invasive method is described for the assessment of angiogenesis in chronic inflammation using laser-Doppler flowmetry. 2. Significant increases in capillary blood flow were seen on days 5 and 7 after induction of subcutaneous granulomatous lesions, as compared with control skin. 3. Changes in blood flow were accompanied by changes in pulsatile flow pattern and by an intense angiogenic response observed by light microscopy. 4. The potential application of laser-Doppler flowmetry to quantitative and qualitative studies of evolving angiogenesis in pathological responses is discussed.