Non-invasive pre-surgical investigation of a 10 year-old epileptic boy using simultaneous EEG-NIRS
Non-invasive pre-surgical investigation of a 10 year-old epileptic boy using simultaneous EEG-NIRS
复制标题
DOI：
10.1016/j.seizure.2008.01.009
复制
发表时间：
2008-09-01
影响因子：
3
通讯作者：
Nguyen, Dang Khoa
中科院分区：
文献类型：
--
作者：
Gallagher, Anne;Lassonde, Marse;Nguyen, Dang Khoa
近红外光谱（NIRS）是一种新的成像技术，在难治性癫痫患者的术前研究中具有潜在的价值。我们同时记录电生理（EEG; Compumedics，美国）和近红外光谱（NIRS； ISS，美国），以检查一个年轻的癫痫男孩（L.H， 10岁）的起病区定位和评估语言偏侧，作为其术前评估的一部分。L.H.进行了长时间的脑电图-近红外光谱记录，同时记录了电临床和电癫痫发作。结果与其他术前技术（SPECT, FDG-PET， EEG-fMRI和EEG-MEG）的结果进行了比较，显示了良好的一致性。为了研究语言侧化，进行了第二次不带脑电图的MRS会话。为此，患者在近红外光谱录音期间进行了分类语言流畅性任务。结果显示这个小男孩的语言功能在左半球占优势。本病例报告表明，多通道脑电图近红外光谱有可能有助于年轻患者的术前调查。(C) 2008英国癫痫协会。Elsevier Ltd.出版。版权所有。
Near-infrared spectroscopy (NIRS) is a novel imaging technique of potential value in the pre-surgical investigation of patients with refractory epilepsy. We recorded simultaneously electrophysiology (EEG; Compumedics, USA) and near-infrared spectroscopy (NIRS; ISS, USA) to examine the localization of the ictal onset zone and assess language lateralization in a young epileptic boy (L.H., 10 years) as part of his pre-surgical evaluation. L.H. underwent a prolonged EEG-NIRS recording while electro-clinical and electrical seizures were recorded. Results were compared to those obtained with other pre-surgical techniques (SPECT, FDG-PET, EEG-fMRI and EEG-MEG) and showed good concordance for ictal onset zone localization. A second MRS session without EEG was carried out in order to investigate language lateralization. For this purpose, the patient performed a categorical verbal-fluency task during NIRS recordings. Results showed left-hemisphere dominance for language function in this young boy. This case report illustrates that multi-channel EEG-NIRS has the potential to contribute favourabLy to pre-surgical investigation in young patients. (C) 2008 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.