Device for rapid quantification of human carotid baroreceptor-cardiac reflex responses.

Device for rapid quantification of human carotid baroreceptor-cardiac reflex responses.
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用于快速量化人类颈动脉压力感受器心脏反射反应的装置。

DOI:
10.1152/jappl.1986.60.2.727
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发表时间:
1986
期刊:
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子:
--
通讯作者:
Halliday,HC
Halliday,HC
中科院分区:
--
文献类型:
--
作者:
Sprenkle,JM;Eckberg,DL;Goble,RL;Schelhorn,JJ;Halliday,HC

文献摘要

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我们设计、构建和评估了一种新装置,可以快速表征人类颈动脉压力感受器-心脏反射反应关系。我们设计这个系统是为了研究宇航员在太空旅行之前、期间和之后的反射反应。该系统包括一个新型紧密密封的硅橡胶颈室、一个步进电机驱动的电镀镍波纹管压力系统,能够提供 +40 至 -65 mmHg 之间连续的 R 波触发颈室压力变化,以及一个基于微处理器的电子系统,用于控制压力阶跃以及分析和显示响应。这一新系统在大多数人类志愿者的一次呼气过程中激发了经典的乙状压力感受器心脏反射反应,其阈值、线性和饱和度范围均不相同。
We designed, constructed, and evaluated a new device to characterize the human carotid baroreceptor-cardiac reflex response relation rapidly. We designed this system for study of reflex responses of astronauts before, during, and after space travel. The system comprises a new tightly sealing silicone rubber neck chamber, a stepping motor-driven electro-deposited nickel bellows pressure system, capable of delivering sequential R-wave-triggered neck chamber pressure changes between +40 and -65 mmHg, and a microprocessor-based electronics system for control of pressure steps and analysis and display of responses. This new system provokes classic sigmoid baroreceptor-cardiac reflex responses with threshold, linear, and saturation ranges in most human volunteers during one held expiration.