Impact of an Individually Tailored Light Mask on Sleep Parameters in Older Adults With Advanced Phase Sleep Disorder.
Impact of an Individually Tailored Light Mask on Sleep Parameters in Older Adults With Advanced Phase Sleep Disorder.
复制标题
单独定制的轻型面罩对患有晚期睡眠障碍的老年人睡眠参数的影响。
DOI：
10.1080/15402002.2018.1557189
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发表时间：
2020
影响因子：
3.1
通讯作者：
Wretman,ChristopherJ
中科院分区：
文献类型：
--
作者：
Figueiro,MarianaG;Sloane,PhilipD;Ward,Kimberly;Reed,David;Zimmerman,Sheryl;Preisser,JohnS;Garg,Seema;Wretman,ChristopherJ
目的本研究调查了通过熟睡者眼睑传递的光是否可能对受到晚期睡眠相位障碍不利影响的老年人造成相位延迟。 参与者 32 名年龄≥ 50 岁、认知能力完整、居住在社区的参与者（20 名女性，12 名男性），匹兹堡睡眠质量指数得分≥ 5（睡眠质量差）完成了这项研究。 方法 这项受试者内、随机、两种治疗交叉设计研究使参与者接受主动“蓝色”（λ max= 480 nm）照明干预或安慰剂“红色”（λ max= 640 nm）通过睡眠期间闭上眼睑进行控制，持续 8 周。睡后 1 小时使用定制光罩进行治疗，每 30 秒发出一系列 2 秒持续时间的光脉冲，持续≤ 2 小时（约 240 个脉冲/晚）。因变量是睡眠和抑郁的主观测量（问卷）和睡眠的客观测量（手腕体动记录仪），使用线性混合模型进行分析，其中治疗、周期和残留作为固定效应。结果体动记录仪分析发现，无论是与基线相比还是相互比较，干预或控制条件对睡眠开始时间、总睡眠时间、睡眠次数或睡眠效率没有影响。然而，研究参与者的主观反应表明，在干预和对照条件下，八项报告的睡眠质量测量中的七项有统计显着性（p<0.05）改善，但两种条件之间没有差异。结论参与者报告了睡眠质量的改善，但在调整周期和残留效应后，干预并没有带来额外的优势。
ObjectiveThis study investigated whether light delivered through the eyelids of sleeping persons might create phase delay in older adults who are adversely affected by advanced sleep phase disorder.ParticipantsThirty-two cognitively intact, community-dwelling participants aged≥ 50 years (20 females, 12 males) with Pittsburgh Sleep Quality Index scores≥ 5 (poor sleep) completed the study.MethodsThis within-subjects, randomized, two-treatment crossover design study exposed participants to an active “blue”(λ max= 480 nm) lighting intervention or a placebo “red”(λ max= 640 nm) control through closed eyelids during sleep for 8 weeks. Conditions were administered 1 hr after bedtime using custom-built light masks delivering a train of 2-s duration light pulses presented every 30 s for≤ 2 hr (approximately 240 pulses/night). Dependent variables were subjective measures of sleep and depression (questionnaires) and objective measures of sleep (wrist actigraphy), analyzed using linear mixed models with treatment, period, and carryover as fixed effects.ResultsThe actigraphy analysis found no effect of the intervention or the control condition on sleep start time, total sleep time, number of sleep bouts, or sleep efficiency, either compared to baseline or to one another. Subjective responses of study participants, however, indicated statistically significant (p< 0.05) improvement in seven of eight reported measures of sleep quality with both the intervention and the control condition, but no difference between the two conditions.ConclusionsThe participants reported improvement in sleep quality, but the intervention did not confer additional advantages after adjusting for period and carryover effects.