Chronic social stress in a changing dietary environment.
Chronic social stress in a changing dietary environment.
复制标题
不断变化的饮食环境中的慢性社会压力。
DOI：
10.1016/j.physbeh.2006.05.026
复制
发表时间：
2006
影响因子：
2.9
通讯作者：
Sakai,RandallR
中科院分区：
文献类型：
--
作者：
Tamashiro,KellieLK;Hegeman,MariaA;Sakai,RandallR
The human population has slowly transformed from the “hunter–gatherer” period to the current environment of high energy consumption, minimal physical activity and a lifestyle that includes stress and anxiety. Modeling the current environment in the laboratory can help to elucidate mechanisms responsible for the development of obesity, diabetes and, ultimately, the metabolic syndrome. Using the visible burrow system (VBS) model of social stress we have begun to examine the short- and long-term consequences of chronic social stress on energy homeostasis. We demonstrated that social stress has significant effects on body weight and body composition such that subordinate rats progressively develop characteristics of obesity and have additionally determined that this occurs, in part, through changes in food intake amount and behavior. Changes in body weight and body composition are similar or greater when animals are maintained on a high fat diet. These data suggest that consumption of a high-fat diet during social stress in the VBS, while it does not appear to affect development of a social hierarchy, enhances the effect that chronic stress has on body composition and may be more representative of what happens in humans in modern society where the typical diet has progressively moved toward higher calorie, high-fat foods.
