Localisation in PET Images: Direct Fitting of the Intercommissural (AC—PC) Line
Localisation in PET Images: Direct Fitting of the Intercommissural (AC—PC) Line
复制标题
PET 图像中的定位：直接拟合连合间 (AC-PC) 线
DOI：
--
复制
发表时间：
1989
影响因子：
6.3
通讯作者：
R. Frackowiak
中科院分区：
文献类型：
--
作者：
Karl J. Friston;R. Passingham;J. Nutt;J. Heather;G. Sawle;R. Frackowiak
描述了一种用于直接从正电子发射断层扫描（PET）图像上的地标（即胼胝体的前部和后部、丘脑和枕极的腹侧）估计连合间线（AC-PC线）的位置的技术。当在磁共振成像（MRI）扫描上测量时，该估计值与通过前连合和后连合中心拟合的真实AC-PC线的关系显示出最小的垂直和角位移。使用回归分析，发现拟合这些点的容易性和可靠性很高。根据Fox等人的方法中使用的假设，验证了这种直接推导的AC-PC线估计值。正如预测的那样，AC-PC线与通过隆突底部的线（GI线）之间的距离与脑总高度的比值为0.21。该技术已通过定位感觉运动皮层的局灶性激活得到进一步验证。该技术进行了讨论的绝对限制，在大脑中使用非侵入性断层扫描技术，特别是PET的结构定位。
A technique is described for estimating the position of the intercommisural line (AC–PC line) directly from landmarks on positron emission tomographic (PET) images, namely the ventral aspects of the anterior and posterior corpus callosum, the thalamus, and occipital pole. The relationship of this estimate to the true AC–PC line, fitted through the centres of the anterior and posterior commissures, showed minimal vertical and angular displacement when measured on magnetic resonance imaging (MRI) scans. Using regression analysis, the ease and reliability of fitting to these points was found to be high. This directly derived AC–PC line estimate was validated in terms of the assumptions used in the method of Fox et al. The ratio of distance between the AC–PC line and a line passing through the base of the inion (GI line) to total brain height was 0.21, as predicted. The technique has been further validated by localizing focal activation of the sensorimotor cortex. The technique is discussed in terms of absolute limits to localization of structures in the brain using noninvasive tomographic techniques in general and PET in particular.