Emotional impairment in Parkinson's disease
Emotional impairment in Parkinson's disease
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DOI：
10.1016/s1353-8020(09)70013-6
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发表时间：
2009-01-01
影响因子：
4.1
通讯作者：
Kobayakawa, Mutsutaka
中科院分区：
文献类型：
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作者：
Kawamura, Mitsuru;Kobayakawa, Mutsutaka
帕金森氏症（PD）患者在疾病的早期阶段可能会表现出情绪障碍。PD患者表现出不利的决策。这与情绪反应减少有关，这是通过皮肤电导反应（SCRs）来测量的。这种减少scr的模式与在杏仁核损伤患者中观察到的相似。在面部表情识别中，PD患者没有表现出杏仁核激活。在另一项研究中，PD患者对不愉快的嗅觉刺激没有表现出杏仁核激活，这在正常对照中观察到。PD患者的情绪障碍可能反映了PD早期的杏仁核功能障碍。(c) 2008 Elsevier Ltd.版权所有。
Patients with Parkinson's disease (PD) may show emotional impairment in the early stages of the disease. PD patients show disadvantageous decision-making. which is related to decreased emotional responses, its measured by skin conductance responses (SCRs). This pattern of decreasing SCRs is similar to that observed in amygdala-damaged patients. In facial expression recognition, PD patients did not show amygdala activation. In another study, PD patients did not show amygdala activations to unpleasant olfactory Stimuli, which were observed in normal controls. Emotional impairment in PD patients may reflect amygdala dysfunction in early PD. (c) 2008 Elsevier Ltd. All rights reserved.