Effect of a nicotine-free inhalator as part of a smoking-cessation programme
Effect of a nicotine-free inhalator as part of a smoking-cessation programme
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DOI：
10.1183/09031936.00109610
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发表时间：
2011-11-01
影响因子：
24.3
通讯作者：
Polosa, R.
中科院分区：
文献类型：
--
作者：
Caponnetto, P.;Cibella, F.;Polosa, R.
戒烟药物不足以解决烟草依赖的行为问题。无尼古丁吸入器是一种塑料装置，可以通过取代一些与吸烟姿势相关的仪式来为条件性吸烟提供应对机制。这项研究评估了使用不含尼古丁的吸入器对提高戒烟计划成功率的效果。 在基线时，对参加戒烟计划的 120 名吸烟者的社会人口因素、吸烟史、抑郁、身体和行为依赖性以及动机进行了评估。参与者被随机分配到两组，无尼古丁吸入器组（PAIPO；Echos Srl，意大利米兰）与参考组。对于整个样本，24 周时 PAIPO 组和参考组的戒烟率没有显着差异。然而，对于基线时格洛弗-尼尔森吸烟行为问卷 (GN-SBQ) 得分较高的个体来说，PAIPO 组的戒烟率 (66.7%) 比参考组 (19.2%) 高出三倍多。 Logistic 模型分析的结果表明，高 GN-SBQ 评分是 PAIPO 组 24 周成功戒烟的强有力的独立预测因素（OR 8.88；95% CI 2.08-37.94）。在戒烟干预中使用无尼古丁吸入器可能是有益的，特别是对于那些处理和操纵香烟在吸烟习惯中起着重要作用的吸烟者。
Smoking-cessation drugs are inadequate at addressing the behavioural component of tobacco dependence. Nicotine-free inhalators are plastic devices that may provide a coping mechanism for conditioned smoking by replacing some of the rituals associated with smoking gestures. This study assessed the effect of using a nicotine-free inhalator to improve success in a cessation programme.At baseline, 120 smokers attending a smoking-cessation programme were assessed for their sociodemographic factors, smoking history, depression, physical and behavioural dependence, and motivation. Participants were randomly assigned to two groups, nicotine-free inhalator group (PAIPO; Echos Srl, Milan, Italy) versus reference group.For the whole sample, no significant difference was found in quit rates at 24 weeks between the PAIPO group and the reference group. However, the quit rate in the PAIPO group (66.7%) was more than three-fold higher than the reference group (19.2%) for those individuals with high Glover-Nilsson Smoking Behavioural Questionnaire (GN-SBQ) scores at baseline. The results of the logistic model analysis indicate that a high GN-SBQ score is a strong independent predictor for successful quitting at 24 weeks (OR 8.88; 95% CI 2.08-37.94) in the PAIPO group.Nicotine-free inhalators may be beneficial when used in the context of smoking-cessation interventions, particularly for those smokers for whom handling and manipulation of their cigarettes plays an important part in the ritual of smoking.