Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases
Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases
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DOI：
10.1111/j.1748-5827.2008.00659.x
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发表时间：
2009-01-01
影响因子：
1.6
通讯作者：
Celona, B.
中科院分区：
文献类型：
--
作者：
Martin, M. W. S.;Johnson, M. J. Stafford;Celona, B.
回顾性分析1993年1月至2006年5月间收集的369只扩张型心肌病犬的临床资料，分析扩张型心肌病犬的临床表现、诊断和存活情况。最常见的受影响的品种是杜伯曼犬和拳击手。95%以上的狗体重超过15公斤，73%为雄性。转诊前体征的中位持续时间为3周，65%的患者出现3期心力衰竭。最常见的症状是呼吸困难（67%）和咳嗽（64%）。大多数犬（89%）在就诊时有心律失常，74%的犬有肺水肿或胸腔积液的放射学体征。中位存活时间为19周。扩张性心肌病主要发生在中型至大型纯种犬中，雄性比雌性更常见。转诊前临床体征的持续时间通常很短，生存时间很短。更多地了解受影响的品种，临床症状和诊断结果可能有助于早期识别这种疾病，通常具有较短的临床阶段。
To review the clinical and diagnostic findings and survival of dilated cardiomyopathy from a large population of dogs in England.A retrospective study of the case records of dogs with dilated cardiomyopathy collected between January 1993 and May 2006.There were 369 dogs with dilated cardiomyopathy of which all were pure-bred dogs except for four. The most commonly affected breeds were dobermanns and boxers. Over 95 per cent of dogs weighed more than 15 kg and 73 per cent were male. The median duration of signs before referral was three weeks with 65 per cent presenting in stage 3 heart failure. The most common signs were breathlessness (67 per cent) and coughing (64 per cent). The majority of dogs (89 per cent) had an arrhythmia at presentation and 74 per cent of dogs had radiographic signs of pulmonary oedema or pleural effusion. The median survival time was 19 weeks.Dilated cardiomyopathy occurs primarily in medium to large breed pure-bred dogs, and males are more frequently affected than females. The duration of clinical signs before referral is often short and the survival times are poor. Greater awareness of affected breeds, clinical signs and diagnostic findings may help in early recognition of this disease which often has a short clinical phase.