Verbal Fluency and Awareness of Functional Deficits in Early-Stage Dementia
Verbal Fluency and Awareness of Functional Deficits in Early-Stage Dementia
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DOI：
10.1080/13854046.2012.665482
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发表时间：
2012-01-01
影响因子：
3.9
通讯作者：
Morris, Robin G.
中科院分区：
文献类型：
--
作者：
Martyr, Anthony;Clare, Linda;Morris, Robin G.
日常生活活动评估是痴呆症诊断的重要组成部分，研究表明功能能力与认知之间存在联系。我们调查了自我和知情者对日常生活工具性活动（iADL）的评分与早期痴呆症患者言语执行功能之间的关系。共有 96 名早期阿尔茨海默病或血管性或混合性痴呆患者及其照顾者完成了功能活动问卷；痴呆症患者还完成了字母流利度测试。字母流利程度与 iADL 的自我评分相关，而 iADL 的知情者评分与痴呆症患者的年龄和简易精神状态检查分数相关。对感知功能的自我评级表明，其损害程度明显低于知情者评级。那些字母流利度受损的人认为自己在 iADL 中比表现更好的人遇到更大的困难。早期痴呆症患者对其 iADL 功能的主观认识水平各不相同，语言产生的困难可能有助于更好地认识 iADL 障碍。
Assessment of activities of daily living is an important element in the diagnosis of dementia, with research suggesting a link between functional ability and cognition. We investigated the relationship between self- and informant ratings of instrumental activities of daily living (iADL) and verbal executive functioning in early-stage dementia. A total of 96 people with early-stage Alzheimer's disease or vascular or mixed dementia and their carers completed the Functional Activities Questionnaire; people with dementia also completed a test of letter fluency. Letter fluency was associated with self-ratings of iADL, while informant ratings of iADL were associated with the age and Mini-Mental State Examination score of the person with dementia. Self-ratings of perceived functioning suggested significantly less impairment than informant ratings. Those with impaired letter fluency rated themselves as having greater difficulties in iADLs than those who performed better. People with early-stage dementia vary in their subjective level of awareness of their iADL functioning, and difficulties with language production may contribute to better awareness of iADL impairments.