Impact of a community-based lifestyle intervention program on health-related quality of life.
Impact of a community-based lifestyle intervention program on health-related quality of life.
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DOI：
10.1007/s11136-016-1240-7
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发表时间：
2016-08
期刊：
影响因子：
--
通讯作者：
Kriska AM
中科院分区：
文献类型：
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作者：
Eaglehouse YL;Schafer GL;Arena VC;Kramer MK;Miller RG;Kriska AM
2型糖尿病和心血管疾病风险因素的存在，或疾病本身，导致成人健康相关生活质量（HRQoL）降低。虽然以社区为基础的生活方式干预计划已被证明是有效的改善这些疾病的危险因素，这些干预措施对HRQoL的影响很少被描述。研究参与团体生活方式平衡计划后HRQoL的变化，该计划是糖尿病预防计划生活方式干预的社区翻译，适用于糖尿病前期和/或代谢综合征成人。参加12个月22次干预计划的受试者（N=223）在基线、6个月和12个月时完成了EuroQol健康问卷（EQ-5D-3L）。线性混合效应回归模型确定了干预后EQ-5D-视觉模拟量表（VAS）和指数评分的变化。平均EQ-5D-VAS在干预后6个月改善了+7.38（SE=1.03），在干预后12个月改善了+6.73（SE=1.06）（均为p<0.0001）。EQ-5D指数值的平均变化分别为+0.00（SE=0.01; NS）和+0.01（SE=0.01; p<0.05）。根据年龄、基线评分和实现干预目标进行调整后，6个月时EQ-5D-VAS的平均变化为+11.83（SE=1.61），12个月时为+11.23（SE=1.54）（均为p<0.0001）。6个月时EQ-5D指数值的校正平均变化为+0.04（SE=0.01），12个月时为+0.05（SE=0.01）（均为p<0.01）。参与社区生活方式干预计划可改善糖尿病前期和/或代谢综合征成人的HRQoL。HRQoL的这些益处，以及改善的临床和行为结果，应该增加这些计划对改善健康的吸引力。
The presence of risk factors for type 2 diabetes and cardiovascular disease, or the conditions themselves, contributes to lower health-related quality of life (HRQoL) among adults. Although community-based lifestyle intervention programs have been shown to be effective for improving risk factors for these diseases, the impact of these interventions on HRQoL has rarely been described. To examine changes in HRQoL following participation in the Group Lifestyle Balance program, a community translation of the Diabetes Prevention Program lifestyle intervention for adults with pre-diabetes and/or the metabolic syndrome. Participants enrolled in the 12-month, 22-session intervention program (N=223) completed the EuroQol Health Questionnaire (EQ-5D-3L) at baseline, 6, and 12 months. Linear mixed effects regression models determined change in EQ-5D-Visual Analog Scale (VAS) and Index scores post-intervention. Mean EQ-5D-VAS improved by +7.38 (SE=1.03) at 6 months and by +6.73 (SE=1.06) at 12 months post-intervention (both; p<0.0001). Mean changes in EQ-5D Index values were +0.00 (SE=0.01; NS) and +0.01 (SE=0.01; p<0.05), respectively. Adjusted for age, baseline score, and achieving intervention goals, mean change in EQ-5D-VAS was +11.83 (SE=1.61) at 6 months and +11.23 (SE=1.54) at 12 months (both; p<0.0001). Adjusted mean change in EQ-5D Index value was +0.04 (SE=0.01) at 6 months and +0.05 (SE=0.01) at 12 months (both; p<0.01). Participation in a community lifestyle intervention program resulted in improved HRQoL among adults with pre-diabetes and/or the metabolic syndrome. These benefits to HRQoL, together with improved clinical and behavioral outcomes, should increase the appeal of such programs for improving health.