Drug Combinations in Breast Cancer Therapy
Drug Combinations in Breast Cancer Therapy
复制标题
DOI：
10.2174/2211738507666190122111224
复制
发表时间：
2019-01-01
影响因子：
--
通讯作者：
Akala, Emmanuel O.
中科院分区：
文献类型：
--
作者：
Fisusi, Funmilola A.;Akala, Emmanuel O.
乳腺癌治疗涉及多学科方法，包括手术、放射治疗、新辅助治疗和辅助治疗。乳腺癌的有效治疗需要最大的治疗效果，最小的不良反应，以确保患者的良好生活质量。精心选择的治疗干预组合为患者提供了从治疗中获得最大益处的机会，同时最大限度地减少或消除复发、耐药性和毒性作用，并确保患者拥有良好的生活质量。这篇综述讨论了乳腺癌治疗的治疗选择和以前开发的各种组合。该综述还将深入了解纳米技术平台在乳腺癌治疗中共同递送治疗剂的潜在应用。
Breast cancer therapy involves a multidisciplinary approach comprising surgery, radiotherapy, neoadjuvant and adjuvant therapy. Effective therapy of breast cancer requires maximum therapeutic efficacy, with minimal undesirable effects to ensure a good quality of life for patients. The carefully selected combination of therapeutic interventions provides patients with the opportunity to derive maximum benefit from therapy while minimizing or eliminating recurrence, resistance and toxic effects, as well as ensuring that patients have a good quality of life. This review discusses therapeutic options for breast cancer treatments and various combinations that had been previously exploited. The review will also give an insight into the potential application of the nanotechnology platform for co-delivery of therapeutics in breast cancer therapy.