Age-specific cancer mortality trends in 16 countries
Age-specific cancer mortality trends in 16 countries
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DOI：
10.1007/s00038-016-0858-0
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发表时间：
2016-09-01
影响因子：
4.6
通讯作者：
Liu, Kristen
中科院分区：
文献类型：
--
作者：
Liu, Lee;Liu, Kristen
这项研究探索了以前鲜为人知的癌症死亡率趋势，重点关注16个国家的年龄和性别差异的变化。时间序列、年龄性别特异性癌症死亡率、全因死亡和人口数据用于统计描述。癌症死亡率（CMR）在11个国家达到峰值，并随着年龄的增长而下降。cmr似乎在较早的时期达到峰值，在较早的时期而不是较晚的时期急剧下降，男性比女性更明显。CMR峰值可能在历史上被推迟了。此外，所有16个国家的“癌症死亡率”（PDC）在60岁左右后大幅下降。中年女性的cmr可能高于男性。绝经前的妇女可能比绝经后的妇女有更高的PDCs。这些发现对文献做出了重大贡献，尽管由于数据质量和可用性，它们的解释和应用存在局限性。未来的研究应该探索这些发现是否适用于其他国家和时期，以及如何适用于其他国家和时期。公共卫生从业人员和政策制定者应考虑针对年龄和性别的策略，以更有效地控制癌症。
This study explored previously little-known cancer mortality trends with a focus on changes with age and sex differences in 16 countries.Time series age-sex-specific cancer mortality, deaths from all causes, and population data were used for statistical description.The cancer mortality rate (CMR) peaked and declined with age in 11 countries. CMRs appeared to peak earlier and decline more dramatically in earlier time periods rather than later periods and for males rather than females. CMR peaking could have possibly been historically delayed. Moreover, "percentage of deaths from cancer" (PDC) in all 16 countries plunged after about age 60. Middle-aged women may have higher CMRs than men. Premenopausal women may have higher PDCs than postmenopausal women.The findings make significant contributions to the literature, though their interpretation and application have limitations due to data quality and availability. Future research should explore if and how the findings apply to other countries and time periods. Public health practitioners and policy makers should consider age-sex-specific strategies for more effective cancer control.