Does socio-demographic status influence the effect of pollens and molds on hospitalization for asthma? Results from a time-series study in 10 Canadian cities
Does socio-demographic status influence the effect of pollens and molds on hospitalization for asthma? Results from a time-series study in 10 Canadian cities
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DOI：
10.1016/j.annepidem.2004.06.001
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发表时间：
2005-03-01
影响因子：
5.6
通讯作者：
Coates, F
中科院分区：
文献类型：
--
作者：
Cakmak, S;Dales, RE;Coates, F
目的：社会地位影响哮喘发病率，但其机制尚不清楚。为了确定是否社会人口统计学影响的易感性，环境空气中的过敏原，我们确定了每日住院治疗哮喘和每日浓度的环境花粉和霉菌在10个加拿大大city.METHODS：每日时间序列分析进行了调整，结果为一周中的一天，温度，大气压，相对湿度，臭氧，一氧化碳，二氧化硫和二氧化氮之间的关联。结果，然后分层的年龄，性别，和邻里家庭教育和income.RESULTS：似乎有年龄和性别之间的关系，吸入性过敏原和哮喘的相互作用。当担子菌数量增加到平均值300个/m3时，年轻男性（13岁以下）的哮喘入院率增加了9.3%（95% CI，4.8%，13.8%），而老年男性的哮喘入院率增加了4.2%（95% CI，-0.1%，8.5%）。女性的情况正好相反，年龄较大组的影响增加：13岁以下女性为2.3%（95% CI，1.2%，5.8%），而年龄较大女性为7.1%（95% CI，4.1%，10.1%）。在最低的，但不是最高的教育group.CONCLUSIONS：我们的研究结果表明，年轻的男性和那些受教育程度较低的家庭可能更容易受到空气过敏原和哮喘住院之间的关联。(c)2004年爱思唯尔公司All rights reserved.
PURPOSE: Social status influences asthma morbidity but the mechanisms are not well understood. To determine if sociodemographics influence the susceptibility to ambient aeroallergens, we determined the association between daily hospitalizations for asthma and daily concentrations of ambient pollens and molds in 10 large Canadian cities.METHODS: Daily time-series analyses were performed and results were adjusted for day of the week, temperature, barometric pressure, relative humidity, ozone, carbon monoxide, sulfur dioxide, and nitrogen dioxide. Results were then stratified by age, gender, and neighborhood family education and income.RESULTS: There appeared to be age and gender interactions in the relation between aeroallergens and asthma. An increase in basidiomycetes equivalent to its mean value, about 300/m(3), increased asthma admissions for younger males (under 13 years of age) by 9.3% (95% CI, 4.8%, 13.8%) vs. 4.2% (95% CI, - 0.1%, 8.5%) for older males. The reverse was true among females with increased effect in the older age group: 2.3% (95% CI, 1.2%, 5.8%) in those under 13 years vs. 7.1% (95% CI, 4.1%, 10.1%) for older females. Associations were seen between aeroallergens and asthma hospitalization in the lowest but not the highest education group.CONCLUSIONS: Our results suggest that younger males and those within less educated families may be more vulnerable to aeroallergens as reflected by hospitalization for asthma. (c) 2004 Elsevier Inc. All rights reserved.