Liver transplantation in the UK.

Liver transplantation in the UK.
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英国的肝移植。

DOI:
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发表时间:
2001
影响因子:
4.3
通讯作者:
J. Buckels
J. Buckels
中科院分区:
医学2区
文献类型:
--
作者:
S. Bramhall;E. Minford;B. Gunson;J. Buckels

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引言 本文对肝移植的实践进行了综述,重点介绍了UK的实践和移植的适应症。 转介和评估 本部分参照英国的实践回顾了肝病患者的转诊和评估过程。 捐献器官 脑干死亡和身体器官捐赠的做法是个别国家特有的,并讨论了捐赠率和可能改进的领域。 手术技巧 回顾了导致肝移植成为一种半选择性手术的技术创新。特别强调了肝切除、裂解和活体相关肝移植的作用,以及这对英国实践的影响。并结合本单位的情况,对肝移植并发症进行了综述。免疫抑制:综述了免疫抑制的演变及其对肝移植的影响,并对未来的治疗方案作了一些参考。 再次移植 对再次移植的作用进行了综述。 结局与生存 回顾了肝移植的结果,特别强调了我们自己的经验。 未来 展望了肝移植的未来。
INTRODUCTION This paper provides a review of the practice of liver transplantation with the main emphasis on UK practice and indications for transplantation. REFERRAL AND ASSESSMENT This section reviews the process of referral and assessment of patients with liver disease with reference to UK practice. DONOR ORGANS The practice of brainstem death and cadaveric organ donation is peculiar to individual countries and rates of donation and potential areas of improvement are addressed. OPERATIVE TECHNIQUE The technical innovations that have led to liver transplantation becoming a semi-elective procedure are reviewed. Specific emphasis is made to the role of liver reduction and splitting and living related liver transplantation and how this impacts on UK practice are reviewed. The complications of liver transplan-tation are also reviewed with reference to our own unit. Immunosuppression:The evolution of immunosuppression and its impact on liver transplantation are reviewed with some reference to future protocols. RETRANSPLANTATION The role of retransplantation is reviewed. OUTCOME AND SURVIVAL The results of liver transplantation are reviewed with specific emphasis on our own experience. FUTURE The future of liver transplantation is addressed.
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