MORPHOGENESIS AND POSSIBLE PRECURSOR LESIONS OF INVASIVE-CARCINOMA OF THE PAPILLA OF VATER - EPITHELIAL DYSPLASIA AND ADENOMA
MORPHOGENESIS AND POSSIBLE PRECURSOR LESIONS OF INVASIVE-CARCINOMA OF THE PAPILLA OF VATER - EPITHELIAL DYSPLASIA AND ADENOMA
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DOI：
10.1016/s0046-8177(85)80018-6
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发表时间：
1985-01-01
期刊：
影响因子：
3.3
通讯作者：
HAFERKAMP, O
中科院分区：
文献类型：
--
作者：
BACZAKO, K;BUCHLER, M;HAFERKAMP, O
本文对58例浸润性乳头癌手术标本进行了组织形态学研究。91.4例病例在癌附近发现管状或绒毛状腺瘤、腺瘤残留物和微腺瘤; 81%的病例在腺瘤结构或表面和导管上皮中存在中度或重度上皮异常增生。浸润性癌由预先存在的粘膜病变如腺瘤或发育不良引起。
Surgical specimens from 58 invasive carcinomas of the papilla of Vater were studied histomorphologically. Tubular or villous adenomas, adenomatous residues and microadenomas were found in the vicinity of the carcinomas in 91.4 of the cases; moderate or severe epithelial dysplasia in adenomatous structures or in surface and ductal epithelium was present in 81% of the cases. Invasive carcinomas arise from pre-existing mucosal lesions, such as adenoma or dysplasia.