Comparison of Body Habitus in Patients With Pulmonary Arterial Hypertension Enrolled in the Registry to Evaluate Early and Long-term PAH Disease Management With Normative Values From the National Health and Nutrition Examination Survey
Comparison of Body Habitus in Patients With Pulmonary Arterial Hypertension Enrolled in the Registry to Evaluate Early and Long-term PAH Disease Management With Normative Values From the National Health and Nutrition Examination Survey
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DOI：
10.4065/mcp.2010.0394
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发表时间：
2011-02-01
影响因子：
8.9
通讯作者：
Badesch, David B.
中科院分区：
文献类型：
--
作者：
Burger, Charles D.;Foreman, Aimee J.;Badesch, David B.
目的：研究大量肺动脉高压（PAH）患者的体重指数（BMI）与肺动脉收缩压之间的相关性。在国家健康和营养检查调查中，将入选评估早期和长期PAH疾病管理登记研究（REVEAL）的第1组PAH患者的BMI与年龄和性别匹配的对照组进行比较（NHANES），以澄清肥胖是否与PAH相关。在REVEAL中通过右侧心脏导管插入术定义PAH诊断。BMI和被认为肥胖（BMI >= 30）和体重不足（BMI>= 30）的患者百分比的差异
OBJECTIVE: To investigate the correlation between body mass index (BMI) and pulmonary artery systolic pressure in a large population of patients with pulmonary arterial hypertension (PAH).PATIENTS AND METHODS: The BMI of patients with group 1 PAH enrolled in the Registry to Evaluate Early and Long-term PAH Disease Management (REVEAL) was compared with that of age- and sex-matched controls in the National Health and Nutrition Examination Survey (NHANES) to clarify whether obesity is linked with PAH. The diagnosis of PAH was defined In REVEAL by right-sided heart catheterization. Differences in BMI and the percentage of patients considered obese (BMI >= 30) and underweight (BMI