Antigenic variation in Mycoplasma hyorhinis: increased repertoire of variable lipoproteins expanding surface diversity and structural complexity.
Antigenic variation in Mycoplasma hyorhinis: increased repertoire of variable lipoproteins expanding surface diversity and structural complexity.
复制标题
猪鼻支原体的抗原变异：可变脂蛋白的种类增加，扩大了表面多样性和结构复杂性。
DOI：
10.1128/iai.61.5.2224-2228.1993
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发表时间：
1993
影响因子：
3.1
通讯作者：
Wise,KS
中科院分区：
文献类型：
--
作者：
Rosengarten,R;Theiss,PM;Yogev,D;Wise,KS
VlpE 是猪鼻支原体可变表面脂蛋白 (Vlps) 家族的新成员。 VlpE 在一些菌株的同基因谱系中显示出表达和大小的表型变异，但在仅表达三种先前已知的 Vlp 的其他菌株的谱系中不存在。一些细胞中四种 Vlp 的表达进一步表明 Vlp 编码序列扩展库的存在和使用，这大大增加了表面多样化的能力。
VlpE is characterized as a new member in a family of variable surface lipoproteins (Vlps) of Mycoplasma hyorhinis. VlpE shows phenotypic variation in expression and size within isogenic lineages of some strains but is absent from lineages of other strains that express only three previously known Vlps. Expression of four Vlps in some cells further indicates the presence and usage of an expanded reservoir of Vlp coding sequences, which greatly increases the capacity for surface diversification.