Supplement Usage Pattern in a Group of COVID- 19 Patients in Tehran.
Supplement Usage Pattern in a Group of COVID- 19 Patients in Tehran.
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DOI：
10.18502/jfrh.v14i3.4668
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发表时间：
2020-09
影响因子：
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通讯作者：
Rezayof E
中科院分区：
文献类型：
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作者：
Bagheri M;Haghollahi F;Shariat M;Jafarabadi M;Aryamloo P;Rezayof E
目的：冠状病毒病 19 (COVID-19) 是一种高度传播的致病性病毒感染，会导致严重急性呼吸系统综合症，并于 2020 年初在世界范围内传播。维生素和微量营养素补充剂对预防和治疗 COVID-19 的作用从科学角度来看似乎具有挑战性。另一方面，专家通常警告不要过度食用这些补充剂。 材料和方法：本研究旨在通过横断面调查来调查 COVID-19 患者既往病史中维生素和微量营养素补充剂的使用模式。 2020年3月至2020年5月期间，共招募了德黑兰伊玛目霍梅尼医院传染病诊所的510名患者。纳入标准是根据临床发现和肺部 CT 扫描疑似感染 COVID-19 的患者。感染患者包括住院患者（171人）和门诊患者（339人）。通过问卷调查收集人口统计信息、临床体征和补充剂模式的使用情况，并对数据进行统计分析。 结果：门诊患者中维生素 D3 摄入量为 30%（103 名患者），住院患者为 16.5%（28 名患者），具有统计学意义（P=0.001）。表明门诊组维生素D3消耗频率高于住院组。这种显着差异也体现在锌的消耗量上，门诊患者为 29 名（9%），住院患者为 4 名（2%）（P=0.007）。多项回归显示，维生素 D3 摄入具有支持作用，可降低疾病恶化和恶化的风险。 （OR=0.291；95% CI 0.102-.0834，P=0.022）。 结论：根据本研究结果和其他研究结果，考虑维生素D3对降低传染病严重程度的支持作用；建议进行适当样本量的临床试验来研究这种维生素在改善呼吸道病毒性疾病方面的功能作用。
Objective: The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection, causes severe acute respiratory syndrome and was spread throughout the world in early 2020. The effects of vitamin and micronutrient supplements on the prevention and treatment of COVID- 19 seems challenging in scientific considerations. On the other side generally, experts warn against over-consumption of these supplements. Materials and methods: This study aimed to investigate the vitamin and micronutrient supplementation usage pattern in past history of patients with COVID-19 via a cross-sectional inquiry. Totally 510 patients referring to the infectious disease clinic of Imam Khomeini Hospital in Tehran from March 2020 to May 2020 were recruited. The inclusion criterion was suspected patients for COVID-19 based on clinical findings and CT scans of the lung. The infected patients included both inpatients (171) and outpatients (339). Demographic information, clinical signs, and the supplement pattern use were collected through a questionnaire and the data were statistically analyzed. Results: Vitamin D3 intake was reported in 30% (103 patients) of outpatients and 16.5% (28 patients) of hospitalized patients, which is statistically significant (P=0.001). It shows that, the frequency of vitamin D3 consumption in the outpatient group was higher than inpatient group. This significant difference has also been shown in zinc consumption, in 29 patients (9%) outpatients versus 4 patients (2%) inpatients were reported (P=0.007). Multi nominal regression showed that vitamin D3 intake has a supportive effect and reduces the risk of exacerbation and worsening of the disease. (OR=0.291; 95% CI 0.102-.0834, P=0.022). Conclusion: According to the results of the present study and the findings of other studies, considering the supportive effect of vitamin D3 in reducing the severity of infectious diseases; Clinical trials with an appropriate sample size are recommended to investigate the functional role of this vitamin in improving viral diseases of the respiratory tract.