The aryl hydrocarbon receptor and the gut-brain axis.
The aryl hydrocarbon receptor and the gut-brain axis.
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芳香烃受体和肠脑轴。
DOI:
10.1038/s41423-020-00585-5
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发表时间:
2021-03
影响因子:
24.1
通讯作者:
Quintana FJ
中科院分区:
文献类型:
--
作者:
Barroso A;Mahler JV;Fonseca-Castro PH;Quintana FJ
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor initially identified as the receptor for dioxin. Almost half a century after its discovery, AHR is now recognized as a receptor for multiple physiological ligands, with important roles in health and disease. In this review, we discuss the role of AHR in the gut–brain axis and its potential value as a therapeutic target for immune-mediated diseases.
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