Canine neoplasia in the UK: estimates of incidence rates from a population of insured dogs
Canine neoplasia in the UK: estimates of incidence rates from a population of insured dogs
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DOI：
10.1111/j.1748-5827.2002.tb00066.x
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发表时间：
2002-06-01
影响因子：
1.6
通讯作者：
Wood, JLN
中科院分区：
文献类型：
--
作者：
Dobson, JM;Samuel, S;Wood, JLN
肿瘤在宠物狗中很常见，但与其他物种一样，在宠物狗中肿瘤发生率的准确数据很少。本研究的目的是记录肿瘤在特定犬群中的发生情况。从130,684只投保狗的数据库中，获取并跟踪了12个月期间与肿瘤或肿瘤样病变的调查或治疗有关的索赔。共有2546项索赔与肿瘤有关，并根据肿瘤部位和类型进行分类。由于投保人群的人口统计数据倾向于年轻动物，因此在计算肿瘤发病率时使用了兽医文献中描述的标准人群。皮肤和软组织是最常见的肿瘤发生部位，标准化发病率为每年每10万只狗1437例，其次是消化道（210例）、乳腺（205例）、泌尿生殖系统（139例）、淋巴（134例）、内分泌（113例）和口咽（112例）。犬皮肤组织细胞瘤是最常见的单一肿瘤类型，标准化发病率为每年每10万只狗337例，其次是脂肪瘤（318例）、腺瘤（175例）、软组织肉瘤（142例）、肥大细胞瘤（129例）和淋巴肉瘤（114例）。这些数据是独一无二的，为今后犬肿瘤的病因学和流行病学研究提供了有价值的基础。
Neoplasia is common in pet dogs but accurate figures for the incidence of tumours in this, as in other species, are sparse. The purpose of this study was to document the occurrence of tumours in a defined population of dogs. From a database of 130,684 insured dogs, claims relating to the investigation or treatment of tumours or tumour-like lesions during a 12-month period were accessed and followed up. A total of 2546 claims were tumour related and were classified according to tumour site and type. Because the demographics of the insured population were skewed towards younger animals, a standard population, as described in the veterinary literature, was used in the calculation of tumour incidence rates. The skin and soft tissues were the most common sites for tumour development, with a standardised incidence rate of 1437 per 100,000 dogs per year, followed by alimentary (210), mammary (205), urogenital (139), lymphoid (134), endocrine (113) and oropharyngeal (112). Canine cutaneous histiocytoma was the most common single tumour type, with a standardised incidence rate of 337 per 100,000 dogs per year, followed by lipoma (318), adenoma (175), soft tissue sarcoma (142), mast cell tumour (129) and lymphosarcoma (114). These data are unique and provide a valuable basis for future research into the aetiology and epidemiology of canine tumours.